Mechanical tension promotes skin nerve regeneration by upregulating nerve growth factor expression-中国期刊网

摘要 Thisstudyaimedtoexploretheroleofmechanicaltensioninhypertrophicscarsandthechangeinnervedensityusinghematoxylin-eosinstainingandS100immunohistochemistry,andtoobservetheexpressionofnervegrowthfactorbywesternblotanalysis.Theresultsdemonstratedthatmechanicaltensioncontributedtotheformationofahyperplasticscarinthebackskinofrats,inconjunctionwithincreasesinbothnervedensityandnervegrowthfactorexpressioninthescartissue.Theseexperimentalfindingsindicatethatthecutaneousnervoussystemplaysaroleinhypertrophicscarformationcausedbymechanicaltension.

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Mechanical tension promotes skin nerve regeneration by upregulating nerve growth factor expression

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Mechanical tension promotes skin nerve regeneration by upregulating nerve growth factor expression

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