简介：PolysaccharidecoatedPLAnanoparticlesbearingaldehydegroupswerepreparedbydialysisofDMSOsolutionofcholesterolhydrophobic-modifieddextranpolyaldehydeandPLAagainstwater.Theaveragediameterofthenanoparticleswasabout160nm,andthesizedistributionwasnearlyhomogenous.ThenanoparticleswerefunctionalizedsimultaneouslywithCD71andEGFRantibodythroughtheSchiff'sbasereaction,andthenradiolabeledwith~(99m)Tc.Afterperfusedtheradiolabelednanoparticlesintotumor-bearing...
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