简介：客观：学习在胸方法的ductalcarcinomainsitu的作为一个预示的因素的组织学的分级的意义：根据凡·奈鈥檚分类，胸的ductalcarcinomainsitu(DCIS)的32个盒子被划分成三个组。结果：低等级(很好区分的、低等级DCIS)12个病人(37.5%)；中间的等级，9个病人(28.1%)；高等级(糟糕区分的DCIS)11个病人(34.4%)。在高等级DCIS之中，histologic子类型是粉刺(9个病人)，micropapillary(1个病人)和固体(1个病人)。在高等级DCIS的积极表示ofc-erbB-2，p53和MIB-1在中间、低的等级DCIS比那高。高等级和低等级DCIS之间的差别是重要的(P<0.05)。表示嗯在高等级，DCIS在中间、低的等级DCIS是比那低的。结论：胸ductalcarcinomainsitu的组织学的分级可以是一个好预示的因素。

简介：ＩＮＳＩＴＵＬＡＢＥＬＩＮＧＡＰＯＰＴＯＳＩＳＩＮＢＲＥＡＳＴＣＡＮＣＥＲＡＳＲＥＬＡＴＥＤＴＯＰＲＯＧＮＯＳＩＳＷｕＪｉｏｎｇ吴炅ＳｈａｏＺｈｉｍｉｎ邵志敏ＪｉａｎｇＭｉｎｇ江明ＨａｎＱｉｘｉａ韩企夏ＺｈａｎｇＴｉｎｇｑｉｕ张廷ＳｈｅｎＺｈｅｎｚ...

简介：Objective:Todeterminethevalueofdiffusion-tensorimaging（DTI）asanadjuncttodynamiccontrastenhancedmagneticresonanceimaging（DCE-MRI）forimprovedaccuracyofdifferentialdiagnosisbetweenbreastductalcarcinomainsitu（DCIS）andinvasivebreastcarcinoma（IBC）.Methods:TheMRIdataof63patientspathologicallyconfirmedasbreastcancerwereanalyzed.TheconventionalMRIanalysismetricsincludedenhancementstyle,initialenhancementcharacteristic,maximumslopeofincrease,timetopeak,timesignalintensitycurve（TIC）pattern,andsignalintensityonFST2WI.Thevaluesofapparentdiffusioncoefficient（ADC）,directionally-averagedmeandiffusivity(Davg),exponentialattenuation（EA）,fractionalanisotropy（FA）,volumeratio（VR）andrelativeanisotropy（RA）werecalculatedandcomparedbetweenDCISandIBC.MultivariatelogisticregressionwasusedtoidentifyindependentfactorsfordistinguishingIBCandDCIS.Thediagnosticperformanceofthediagnosisequationwasevaluatedusingthereceiveroperatingcharacteristic（ROC）curve.ThediagnosticefficaciesofDCEMRI,DWIandDTIwerecomparedindependendyorcombined.Results:EAvalue,lesionenhancementstyleandTICpatternwereidentifiedasindependentfactorfordifferentialdiagnosisofIBCandDCIS.ThecombinationdiagnosisshowedhigherdiagnosticefficacythanasingleuseofDCE-MRI（P=0.02）,andtheareaofthecurvewasimprovedfrom0.84（95%CI,0.67-0.99）to0.94（95%CI,0.85-1.00）.Conclusions:QuantitativeDTImeasurementasanadjuncttoDCE-MRIcouldimprovethediagnosticperformanceofdifferentialdiagnosisbetweenDCISandIBCcomparedtoasingleuseofDCE-MRI.