简介：Marius山是月亮的靠近的一边上的一个暴烈的高原。它具有为它暴烈的特征的高集中的大兴趣，包括屋顶，锥，山脉，和rilles。然而，这个高原的词法、按年代先后的特征很好没由于早使命数据的低分辨率被学习。这研究在月亮的侦察Orbiter(LRO)(0.5m/pix)上在Selene-1(10m/pix)和狭窄的角度照相机(NAC)上用地面照相机(TC)的最近的高空间的分辨率图象描述暴烈的特征的详细形态学。我们这里报导象熔岩试管的天窗和残余那样的一些新结构。我们与ClementineUVVIS数据划分了幽灵似地同质的区域并且在每光谱的联合起来与月亮的Orbiter(LO)IV和TC图象做了坑尺寸频率分发(CSFD)大小。我们首先报导1.10的绝对模型年龄为Marius暗岩1的Ga，为Flamsteed暗岩的1.49Ga，和为Schiaparelli的1.46Ga暗岩。另外，我们识别了几个更年轻的熔岩事件：他们是Marius暗岩2(814妈)，媒介到低钛暗岩(949妈)，和无差别的中等的钛暗岩(687妈)。最后，我们为Marius山的形成建议一种披风羽毛情形，它能解决以前的模型的矛盾。

简介：Datingofmetallicoredepositshasbeenoneoftheproblemsconcernedwithbyoregeologistsformanyyears.TheestablishmentoftheRe-OsIsotopeLaboratoryattheInstituteofRockandMineralAnalysis,ChineseAcademyofGeologicalSciences,hasprovideduswithanewtechniquetocarryoutgeochronologicalstudiesofmolybdenumores.AsoneofthemostimportantRe-bearingminerals,molybdenitecontainsalmostnocommonosmium,but^187Oswasderivedcompletelyfromdecayof^187Re,with^187OscontentasthefunctionofRecontentinthemineral.AnID-ICP-MStechniquehasbeenusedinthisstudy,andRe-Osisotopicagesofseverallargemolybdenumdepositsofdiffer-enttypesfromtheEastQinlingmolybdenumbelthavebeendetermined.ItisindicatedthattheHuanglongpucarbonatitevein-typemolybdenum-(lead)deposithasaRe-OsagecorrespondingtoIndosinian,whiletherestporphyry-typemolybdenumdepositsandporphyry-skarn-typemolybdenum-(tungsten)depositshaveRe-OsagescorrespondingtoYenshanian.

简介：AtthebeginningofsevencenturyB.C,astheconflictsbetweenvassalsweregettingfierce,abodyguardwithforceandcouragewasneededbythemonarchoffeudalChina.Thenstabber-thefirsttypeofthehanger-onofanaristocratappeared.

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简介：RecentexaminationandassessmentabouttheporphyrycopperdepositsinGangdisemetallogenicbeltinsouthernTibethaverevealedthattheseporphyrycopperdepositsarehighlyprospective.SeveralmethodshavebeenusedfortheisotopicdatingoftheQulong,TinggongandChongjiangporphyrycopperdeposits,whichgivesoutapetrogeneticageof17.58±0.74Ma(single-zircondatingofSHRIMP),ametallogeneticageof15.99±0.32Ma(Re-Osisochrondating)andanalterationagerangingbetween12.00Maand16.5Ma(K-Ardating).Themetallogeneticageisingeneralagreementwiththealterationage.ItcanbeseenthatthepetrogeneticandmetallogeneticagesfortheporphyrycopperdepositsinGangdisemetallogenicbeltarenoticeablylaterthantheageforthecollisionalgraniticintrusioninthisbelt.Theauthorscontendthattheporphyrycopperdepositsinthestudyareawereformedinapost-collisionalextensionaltectonicsetting,andarecloselyrelatedtothedelaminationofthemountainrootsoftheorogenicbeltsandtheupliftingoftheQinghai-TibetPlateau.

简介：Exclosureisamethodofrehabilitatingdegradedlandsbyprotectingthemfromtheinterferenceofanimalsandfromhumanencroachment,andisusedtoregeneratenativevegetationasawaytoreducesoilerosion,increaserainwaterinfiltrationandprovidefodderandwoodybiomassindegradedgrazinglands.Therefore,westudiedwoodyplantstructure,diversityandregenerationpotentialsin5-and10-yeargrazingexclosuresincomparisonwithopengrazedsitesinasemi-aridenvironment.Dataonspeciesdiversity,abundance,structure,basalarea,frequency,density,andregenerationstatuswerecollectedfrom270sampleplots.Forty-onewoodyspeciesrepresenting20familieswereidentified,with18,28and38speciesfoundinopengrazedareas,andin5-and10-yeargrazingexclosures,respectively.The10-yeargrazingexclosureshadahigher(P<0.05)speciesrichnessandplantdensitiescomparedtothe5-yeargrazingexclosuresandtheopengrazedareas.ThepopulationstructureandregenerationstatusofwoodyspeciesinbothgrazingexclosuresshowedaninvertedJ-shape,indicatingahealthyregenerationstatus,whereashamperedregenerationwasobservedinopengrazedareas.Theestablishmentofgrazingexclosureshadpositiveeffectsinrestoringwoodyplantdiversityandimprovingvegetationstructureandregenerationpotentialsofdegradedgrazinglands.

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简介：ThedeterminationofLuzhou-flavorliquoragesiscarriedoutbythree-dimensionalfluorescencespectroscopycombinedwithnon-negativematrixfactorization(NMF).37samplesofagedliquorswithweightedagesof15,20and25yearswerepreparedbyblendingthreeLuzhou-flavororiginalbaseliquorswithstorageagesof10,20and30yearsindifferentproportions.Thefluorescencespectraofthesamplesweremeasured,andthenfactorizedintobasismatrixandcoefficientsmatrixbymultiplicativeiterativeNMF.Thefluorescencespectra,reconstructedfromthebasismatrix,aresimilartotheoriginalspectra.Thecoefficientsmatrixistakenastheinputofsupportvectormachine(SVM)toestablishapredictionmodelforthedeterminationofliquorages.Comparedwiththeprincipalcomponentanalysis,thepredictionmodelbasedonSVMhasapredictedaccuracybetterthan91.7%.Thismethodcanprovidehelpsforthemarketsupervisionontheagedliquors.

简介：GinsenosidesRg1,Re,Rb1,Rc,Rb2,Rb3,andRdindifferentpartsoftheAmericanginsengplantwereinvestigated.Theextractionprocesswasapressurizedmicrowave-assistedextraction(PMAE).Thesevenginsenosideswereseparatedanddeterminedbyhigh-performanceliquidchromatography(HPLC)withaultraviolet(UV)detector,at203nm.TheexperimentresultsshowedsignificantvariationsintheindividualginsenosidecontentsoftheAmericanginsengindifferentpartsandagesoftheplant.Theresultsdemonstratedthattheleaves,roothairs,andrhizomesofPanaxquinquefoliusL.containedhigherginsenosidecontents,followedbythemainrootsandstems.TheleavescontaineddramaticallyhigherlevelsofginsenosideRg1,Rb3,andRdthantheotherfourparts.HighercontentsofRb1andRewerepresentinthemainroots,roothairs,andrhizomes.Theamountofginsenosidecontentinthestemswasthelowest.Thetotalcontentofthesevenginsenosidesinmainroots,roothairsandrhizomesincreasedwiththeageoftheplant.Incontrast,theginsenosidecontentsintheleavesandstemsdecreasedwithayearofgrowth.

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简介：RicecropgrowthandyieldinthenorthIranareaffectedbycropdurationandphenology.ThepurposeofthisstudywastocalibrateandvalidatetheORYZA2000modelunderpotentialproductionbasedonexperimentaldataforsimulatingandquantifyingthephenologicaldevelopment,cropdurationandyieldpredictionofricecropinfluencedbydifferentseedlingages.InordertocalibrateandvalidatethecropparametersofORYZA2000model,atwo-yearfieldexperimentwasconductedunderpotentialgrowthconditio...

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简介：Geza岛弧是一个著名矿化作用集中区域，在西藏的高原的东方边缘的Sanjiang领域的部分。在最近的年里，几迟了的Yanshanian花岗石的侵入和联系存款在这个区域被发现了，在桃花源，区域是其一最大Laba铝存款。以前的研究建议预定Laba矿化作用是85±2妈。然而，granodioritic斑岩的年龄仍然保持未知。在这研究，从忍受辉钼矿的granodioritic斑岩的三件样品锆石标明日期的LA-ICP-MSU-Pb与85.00±的产生日期一起被进行了0.23妈(MSWD=0.58)，85.28±0.28妈(MSWD=1.12)，并且84.83±0.26妈(MSWD=0.79)分别地，显示这些granodioritic斑岩在∼85附近在迟了的Yanshanian形成了妈。与矿化作用的地质的特征结合了，时间地，Laba存款遗传上空间地与granodioritic斑岩被联系。另外，Laba存款的年龄与另外的迟了的Yanshanian侵入和矿化作用一致，建议矿化作用可能在在迟了的白垩纪期间的intra板extensional环境下面被产生。

简介：ObjectiveTheMiao’ershan–Yuechenglingcompositegranite,locatedinnorthernGuangxiatthewesternsectionoftheNanlingRange,isamulti-periodandmulti-stagecompositeplutonwithanexposedareaofmorethan3000km2(Fig.1).PaleozoicandProterozoicstrataareexposedaroundit,andmagmaticactivitiesmainlyoccurredduring

简介：Dalbergia印度黄檀Roxb。是南亚的有希望的多种用途的树种类之一。大多数D的种植园。从种子的印度黄檀由于死回来疾病正在面对严重威胁，它最终在一些月以内引起这个潜在的树种类的死亡。植物的繁殖能避免死回来疾病。D的不同年龄组的三十棵母亲树。印度黄檀为从D评估树枝剪样的rooting行为被选择。由植物生长素影响了的印度黄檀(在100点的IAA或IBA，200，500mg敧敭瑮瀠潲潴潣獬愠敲渠敥敤?潦?潣獮牥慶楴湯漠?桴?灳'虜瑂

简介：目的探讨糖基化产物（AGEs）、氧化应激与糖尿病肾病（DN）的关系和金雀异黄素（Gen）改善肾功能的保护机制。方法采用腹腔注射链脲佐菌素建立糖尿病大鼠模型，观察Gen对糖尿病大鼠血糖、肾功能、AGEs、超氧化物歧化酶(SOD)等的影响。结果实验8周后，糖尿病大鼠空腹血糖、尿蛋白、血肌酐、尿素氮及AGEs、丙二醛（MDA）含量明显增高，而体重、肌酐清除率、肾组织SOD活力显著下降；Gen能降低糖尿病大鼠的血糖、尿蛋白、血肌酐、尿素氮、MDA、AGEs含量，增加糖尿病大鼠的肌酐清除率、SOD、总抗氧化能力。结论AGEs增多和氧化应激增强与DN的发生密切相关，Gen能降低糖尿病大鼠的血糖水平、抑制肾脏的氧化应激、阻碍糖基化反应，减轻或延缓DN的发生。

简介：前列腺癌症(PCa)是年龄相关的疾病，并且stromal微型环境在prostatic起一个重要作用恶意的前进。然而，在在年轻、旧的织物在场的前列腺stromal房间的差别仍然是阴暗的。我们从改变年龄的施主的正常prostatic外设地区(PZ)建立了主要有教养的stromal房间并且从旧施主发现那有教养的stromal房间(PZ旧)更多被扩大并且比那些多角形从年轻施主(PZ年轻)。基于immunocytochemical和ultrastructural分析，而且，stromal房间的部件与增加施主年龄从成纤维细胞的一个多数改变了到成纤维细胞和myofibroblasts的混合物。用一在vitro文化系统三维，我们发现PZ旧的stromal房间能提高cocultured的增长，迁居和侵略良性的BPH-1和PC-3房间。用一在里面vivo织物再结合系统，我们也发现PZ旧的stromal房间是比在由高经过的BPH-1房间支持瘤形成的PZ年轻的房间更有效的(>；100)并且PC-3房间。到这些的可能的机制完成的探查，我们执行了cDNAmicroarray分析并且在PZ旧的房间介绍了509upregulated基因和188downregulated基因。在改变的基因之中，我们发现了基因为能够影响邻近的上皮的房间的paracrine因素的一个子集编码；这些包括hepatocyte生长因素(HGF)，成纤维细胞生长因素5(FGF5)，像胰岛素的生长因素2(IGF2)，像胰岛素的生长因素绑定蛋白质4(IGFBP4)，IGFBP5和矩阵metallopeptidase1(MMP1)。在这些基因的表示的变化被量的即时聚合酶链反应(PCR)进一步证实，西方的弄污和连接酶的immunosorbent试金。总的来说，我们的调查结果显示从旧施主的前列腺PZ的stromal房间是比从在支持邻近的上皮的房间的恶意的过程的年轻施主的类似的房间更活跃的。在为PCa的预防的新潜在的策略的这发现提示。

简介：ObjectiveThepotassicandultrapotassicrocksrelatingtotheIndia-EurasiacollisionandcontinualplateconvergencearewidelydistributedintheLhasaterrane.TheserocksareveryimportanttounderstandthedeepprocessesoftheIndia-EurasiacollisionandtheupliftandevolutionoftheTibetanPlateau.Althoughhigh-potassicvolcanicrocksarealsoexposedinthewesternLhasaterrane,theirformation

简介：摘要目的探讨糖尿病肾病(diabetes kidney disease, DKD)模型小鼠肠肾组织晚期糖基化终产物(advanced glycosylation end product, AGEs)/钠-葡萄糖1型协同转运体(sodium-glucose cotransporter-1, SGLT-1)及肠道菌群的变化。方法选取KKay小鼠20只，分为糖尿病组(DM组，n＝10)和糖尿病肾病组(DKD组，n＝10)，检测血清AGEs、脂多糖(lipopolysaccharide, LPS)、肿瘤坏死因子α(tumor necrosis factor-α，TNF-α)、白细胞介素6(intereukin-6，IL-6)的浓度，Western blot技术检测AGEs及SGLT-1在肠肾组织的蛋白表达，高通量测序分析肠道菌群的差异。结果与DM组比较，DKD组小鼠炎症指标TNF-α、IL-6及内毒素水平升高，血清、肠肾组织中AGEs的含量升高、SGLT-1在肠道组织含量升高(P<0.05)。Metastats检验显示DKD组门水平上疣状微生物菌门丰度减低，变形菌门丰度升高(P<0.05)，气单胞菌属、肠杆菌属、摩根氏菌属、克雷伯菌属、沙雷氏菌属、伯克霍尔德菌属等G-菌相对优势分布，阿克曼氏菌属丰度显著低于DM组(P<0.05)。结论DKD小鼠肠道AGEs的升高可能诱发肠道菌群失调，尤其是变形菌门升高、疣状微生物菌门及阿克曼氏菌属降低，导致G-菌渗漏入血产生肠源性内毒素血症引起炎症反应，这可能是DKD发病的重要因素。SGLT-1在肠道组织升高，这可能进一步参与DKD的病情发展。

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