简介：AnewclassofcrosslinkingpolyphosphatesweresynthesizedandcharacterizedbyIR^1HNMR,^31PNMRspectroscopyaswellaselementalanalysis.InvitrodegradationofthepolyphosphatesobtainedandthereleaseofantineoplasticdrugMethotrexate(MTX)andcontraceptiveLevonorgestrel(LNG)byusingthesepolymersasmatrixwerestudied.ZeroorderreleaseratewasobservedinthecaseofLNGrelease.

简介：这研究的目的是评估crosslinking效果一自然地bioprosthetic心阀门的材料上的crosslinkingreagent-procyanidins(PA)。在由procyanidins修理牛的心囊的纸巾以后，crosslikng特征，机械性质，在vitro，酶的降级抵抗，hydrophilicity和溶血测试被检验。结果证明有glutaraldehyde(GA)或procyanidins的生物织物的固定象在vitro一样增加了它的变性作用温度，表面hydrophilicity和机械性质酶的降级抵抗。在变性作用温度没有重要差别，机械性质，hydrophilicity并且在里面在glutaraldehyde和procyanidins之间的酶的降级修理了的vitro纸巾。然而，procyanidins的最终的张力的力量修理了纸巾比glutaraldehyde显著地优异固定纸巾。溶血测试证明procyanidins的那溶血率修理了纸巾比glutaraldehyde的修理纸巾的低。这研究显示出那个procyanidins罐头交叉连接它牛的pericardiaa有效地没有毒性。我们的结果建议这个方法可能是为bioprosthetic心阀门的准备的一条有用途径。

简介：Polydimethylsiloxane(PDMS)rubberlatexwithtwosortsofsensitizers,trimethylolpropanetri-methacrylate(TMPTMA)anddiethyleneglycoldi-acrylate(DEGDA),wasirradiatedwithγ-raysandelectronbeamsinvariousconditions.TheradiationcrosslinkingreactionofPDMSoccursintheinnerphaseofthelatexandisrelativelyisolatedfromthewaterphase.Thereforetheoxygenandtheradicalsproducedbytheradiolysisreactionofwateralmosthavenoeffectonthecrosslinkingreactionofpolymer.TheexperimentaldatacorrespondwiththeCharlesby-Pinnerrelationshipinthemain.Thegelationdoses,degreeofcrosslinkinganddegradationaswellasGvaluesofcrosslinkingwerecalculated.Fromthem,thesensitizationcoefficientswerederivedtoofferaquantitativemeasurementoftheenhancingeffectofsensitizerontheradiationcrosslinking.

简介：Inthispaper,radiation-inducedcrosslinkingmechanismandcharacterizationofthecrosslinkingdensityofF-40andF-4byX-rayphotoelectronspectroscopy(XPS)havebeenstudied.ThedoseofgelationofF-40obtainedfromXPSis4.1×10~4Gy.ItisfoundthatcrosslinkingdensityisthelargestintherangeofcertaindoseforF-40andF-4.

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简介：UltraHighMolecularWeightPolyethylene(UHMWPE)hasbeenwidelyusedasabearingmaterialforartificialjointreplacementoverfortyyears.Itisusuallycrosslinkedbygammaraysirradiationbeforeitsimplantationintohumanbody.Inthisstudy,UHMWPEandUHMWPE/nano-hydroxyapatite(n-HA)compositewerepreparedbyvacuumhot-pressingmethod.Thepreparedmaterialswereirradiatedbygammaraysinvacuumandmoltenheattreatedinvacuumjustafterirradiation.Theeffectoffillingn-HAwithgammairradiationontribologicalpropertiesofUHMWPEwasinvestigatedbyusingfrictionandwearexperimentalmachine(modelMM-200)underdeionizedwaterlubrication.Micro-morphologyofwornsurfacewasobservedbymetallographicmicroscope.Contactangleandhardnessofthematerialswerealsomeasured.Theresultsshowthatcontactangleandhardnessarechangedbyfillingn-HAandgammairradiation.Frictioncoefficientandwearrateunderdeionizedwaterlubricationarereducedbyfillingn-HA.Whilefrictioncoefficientisincreasedandwearrateisreducedsignificantlybygammairradiation.Thewornsurfaceofunfilledmaterialismainlycharacterizedasadhesivewearandabrasivewear,andthatofn-HAfilledmaterialismainlycharacterizedasabrasivewear.Aftergammairradiation,thedegreesofadhesiveandabrasivewearforunfilledmaterialandabrasivewearofn-HAfilledmaterialaresignificantlyreduced.Unfilledandfilledmaterialsafterirradiationaremainlyshownasslightfatiguewear.TheresultsindicatethatUHMWPEandUHMWPE/n-HAirradiatedatthedoseof150kGycanbeusedasbearingmaterialsinartificialjointsforitsexcellentwearresistancecomparedtooriginalUHMWPE.

简介：在这个工作，最佳的electrospinningtrans聚异式戊二我烯(TPI)调节答案不过被评估它的更低的玻璃转变温度比房间温度。随后，TPInonwovens的化学crosslinking被在nanofiber结构的坚持的情况中在高温度硫化第一调查。为这个目的，治好TPI的代理人被co-electrospinning在TPInanofibers嵌入，然后protect层在由过滤在140160点在橡胶的硬化前通过TPInonwoven的明胶答案的TPInanofibers上是涂的

简介：Aseriesofacrylic-basedsuperabsorbentresinsweresynthesizedbyinversesuspensionpolymerization,usingpotassiumpersulfateastheinitiator,N,N′-methylenebisacrylamide(BIS)anddivinylbenzene(DVB)asthemultiplecrosslinkingagents.ThemorphologyoftheresultingsuperabsorbentresinsrevealedbySEMdemonstratedthatahardshelllayerwasindeedformedduetosurfacecrosslinking.Theswellinganddeswellingproperties,andthemechanicalstrengthofsuperabsorbentswereinvestigated.TheresultsindicatedthattheaddingtimeofDVBandtheamountofDVBparticipatedinthecrosslinkingshowasignificantinfluenceonthepropertiesofsuperabsorbents.WhenDVBwasaddedinpolymerizationlater,theamountofDVBparticipatedinreactiondecreasesandthesurfacecrosslinkedshellbecomesthinner.ItissuitableforDVBtobeintroducedinthelaterstageofthepolymerizationprocess,becausetheabsorptionrateofresinisefficientlyimprovedinconjunctionwithhigherwaterabsorption.Furthermore,itwasfoundthatthemechanicalstrengthofswollensuperabsorbentwithsurfacecrosslinkingwasindeedenhancedincomparisonwiththatoftheconventionalone.

简介：有在170，180和190的温度从0.1wt%到1.0wt%的低过氧化物集中的高密度聚乙烯的Crosslinking反应

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简介：AIMTo在transepithelial以后评估组织学的变化用在试验性的兔子研究的部分厚度excimer激光脱离或上皮的乙醇申请的角膜的crosslinking(CXL)。

简介：Metalion-imprintedlycrosslinkedchitosanresin1andresin2werepreparedbytheuseofCu^2+andNi^2+astemplateionsandglutaraldehydeascrosslinkingagent,respectively,ThroughinvestigationontheadsorptioncapactiesandbindingconstantsforCu^2+,Ni^2+andCo^2+ionsonchitosanresins,resin1andresin2exhibittheadsorptionselectivityforthemixturesolutionof1L1Cu^2+andNi^2+ions.Theadsorptionselectivityofmetalion-imprintedresinsfortheirtemplateionsinmuchhigherthanthatofuncrosslinkedchitosanresin.

简介：AIM:Toevaluatetheefficacyandsafetyofcornealcollagencrosslinking(CXL)topreventtheprogressionofpost-laserinsitukeratomileusis(LASIK)cornealectasia.·METHODS:Inaprospective,nonrandomized,single-centrestudy,CXLwasperformedin20eyesof11patientswhohadLASIKformyopicastigmatismandsubsequentlydevelopedkeratectasia.Theprocedureincludedinstillationof0.1%riboflavin-20%dextranesolution30minutesbeforeUVAirradiationandevery5minutesforanadditional30minutesduringirradiation.Theeyeswereevaluatedpreoperativelyandat1-,3-,6-,and12-monthintervals.Thecompleteophthalmologicexaminationcompriseduncorrectedvisualacuity,bestspectacle-correctedvisualacuity,endothelialcellcount,ultrasoundpachymetry,cornealtopography,andinvivoconfocalmicroscopy.·RESULTS:CXLappearedtostabiliseorpartiallyreversetheprogressionofpost-LASIKcornealectasiawithoutapparentcomplicationinourcohort.UCVAandBCVAimprovementswerestatisticallysignificant(P<0.05)beyond12monthsaftersurgery(improvementof0.07and0.13logMARat1year,respectively).Meanbaselineflattestmeridiankeratometryandmeansteepestmeridiankeratometryreduction(improvementof2.00and1.50diopters(D),respectively)werestatisticallysignificant(P<0.05)at12monthspostoperatively.At1yearafterCXL,meanendothelialcellcountdidnotdeteriorate.Meanthinnestcorneapachymetryincreasedsignificantly.·CONCLUSION:Theresultsofthestudyshowedalong-termstabilityofpost-LASIKcornealectasiaaftercrosslinkingwithoutrelevantsideeffects.Itseemstobeasafeandpromisingproceduretostoptheprogressionofpost-LASIKkeratectasia,therebyavoidingordelayingkeratoplasty.