简介：1.有时这两个词大致同义,只是位置不同:all要放在冠词、指示代词、物主代词等之前,而whole应放在这些词之后。allthefamily/thewholefamily全家2.在复数名词前一般用all,在单数可数名词前一般用whole.

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简介：Objective:Weinvestigatedthecorrelationbetweenthenumberofcirculatingtumorcells(CTCs)andwholebodymetabolictumorvolume(WBMTV)measuredby18F-fluorodeoxyglucose(FDG)positronemissiontomography/computedtomography(PET/CT).TheaimwastoevaluatethevalueoftheincorporationofCTCnumberandWBMTVintheprognosticpredictionofstageIIIsmall-celllungcancer(SCLC).Methods:Onehundredandtwenty-ninepatientswereenrolledinthisstudy.Allpatientsweretreatedwithfourcyclesofaplatinum-basedregimenandconcurrentchestirradiation,followedbyprophylacticcranialirradiation.BloodsamplesforCTCanalysiswereobtainedfrom112patientsbeforetheinitiationofchemotherapy(asabaseline),aftercycle1andaftercycle4.CTCsweremeasuredusingtheCELLSEARCH?system.ThepatientsunderwentpretreatmentFDGPET/CTWBMTV,whichincludedallmalignantlesions.TheSpearmanranktestwasusedtodeterminethecorrelationamongCTCcounts,WBMTVanddiseasestage.Overallsurvival(OS)andprogression-freesurvival(PFS)curveswereproducedusingtheKaplan-Meiermethod,andsurvivaldifferencesbetweengroupswereassessedbythelog-ranktest.Results:ThenumberofCTCsatbaselinedidnotcorrelatewithWBMTVbeforetheinitiationoftherapy(P=0.241).ThenumberofCTCsatbaselineandtheWBMTVbeforetheinitiationoftherapywereindependentrelevantfactorsforPFSandOS.Thesubgroupanalysis(GroupA:CTCcount>19.5andaWBMTV>266.5cm^3;GroupB:CTCcount>19.5andaWBMTV≤266.5cm^3;GroupC:CTCcount≤19.5andaWBMTV>266.5cm^3;GroupD:CTCcount≤19.5andaWBMTV≤266.5cm^3)showedthatthedifferenceswerestatisticallysignificantinthemedianPFS(GroupAvs.D,P<0.001;GroupBvs.D,P=0.018;GroupCvs.D,P=0.029)andinthemedianOS(GroupAvs.D,P<0.001;GroupBvs.D,P=0.012).Conclusions:CTCnumberandWBMTVarerelatedtoprogressionanddeathinpatientswithSCLC.TheincorporationofCTCnumberandWBMTVscanscanprovideadetailedprognosticpredictionforSCLC.

简介：Post-collisionalvolcanicrocksofMesozoicageoccurintheregionsadjacenttoGerze,partofthesouthernQiangtangTerraneofnorthernTibet,China.Geochronological,geochemical,andwholerockSr-Ndisotopicanalyseswereperformedonthevolcanicrockstobettercharacterizetheiremplacementageandmodelsfortheirorigin.Laserablation-inductivelycoupledplasma-massspectrometry(LA-ICP-MS)U-Pbzirconanalysesyieldedconsistentagesrangingfrom123.1±0.94Mato124.5±0.89Maforsixvolcanicrocksfromthestudyarea.Theintermediatevolcanicrocksbelongtothealkalineandsub-alkalinemagmaseriesintermsofK2O+Na2Ocontents(5.9%–9.0%),andtotheshoshoniticandcalc-alkalineseriesonthebasisoftheirhighK2Ocontents(1.4%–3.3%).TheGerzevolcanicrocksarecharacterizedbytheenrichmentoflightrareearthelements[(La/Yb)N=34.9–49.5]andlarge–ionlithophileelements(e.g.,Rb,Ba,Th,U,K,Pb,andSr),slightlynegativeEuanomalies(Eu/Eu*=0.19–0.24),andnegativeanomaliesinhighfieldstrengthelements(e.g.,Nb,Ta,HfandTi),relativetoprimitivemantle.Thesamplesshowslightlyelevated(87Sr/86Sr)ivaluesthatrangefrom0.7049to0.7057,andlowεNd(t)valuesfrom-0.89to-2.89.Theseresultssuggestthatthevolcanicrocksstudiedderivedfromacompositionallyheterogeneousmantlesourceandthattheirparentmagmaswerebasaltic.Themoremafic,parentalmagmastotheGerzevolcanicrockslikelyunderwentfractionalcrystallizationofclinopyroxene,hornblende,biotite,andpotassiumfeldspar,duringascent,withlittletonocrustalcontamination,priortotheireruption/emplacement.Whilethesevolcanicrocksexhibitgeochemicalsignaturestypicalofmagmasformedinadestructiveplate-marginsetting,itisplausiblethattheirmantlesourcemightalsohaveacquiredsuchcharacteristicsinanearlierepisodeofsubduction.