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  • 简介:Thisstudyexaminestheeffectsofxenograftsofmicroencapsulatedbovinechromaffincells(BCCs)ontherotationalbehaviorofhemiparkinsonianmonkeyrecipients.Inaddition,itdeterminesthecontentofmonoamineneurotransmittersandtheirmajormetabolitesintheneostriatuminhemiparkinsonianmonkeys.Thehemiparkinsonianmodelinmonkeyswasinducedbyaunilateralintracarotidinjectionofmethyl-phenyl-tetrahydropyridine(MPTP).UnencapsulatedBCCs(n=2),BCCsmicroencapsulated(n=6)inalginate-polylysine-alginate(APA)membranesaswellasemptymicroencapsules(n=1)weregraftedintotheneostriatumofthehemiparkinsonianmonkeys.

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