学科分类
/ 2
35 个结果
  • 简介:Theconventionalbypassdesignistoimplantagraftonthestenosedhostarteryallowingbloodtoflowbypassthestenoticartery.However,restenosisisachallengingproblemwhichfinallyresultsinreoperation.Thepurposeofthispaperistoproposeanewbypassgraftdesignofcoronaryarterywithanassistantgraftforthetreatmentofcoronaryarterystenosis.AnadditionalassistantgraftwasemployedinthenewdesigncomparedwiththeconventionalETSanastomosis.Numericalsimulationswereperformedbymeansoffinitevolumemethodusingcomputationalfluiddynamics(CFD)solver.ResultsdemonstratedthatthenewanastomosesmodelprovidedamoresmoothflowatthedistalETSanastomosiswithoutanystagnationpointonanastomoticbedandvortexformationintheheelregion.Oscillatoryshearindex(OSI)andtime-averagedwallshearstressgradient(TAWSSG)atthearterybedofthedistalETSanastomosiswerereduced.Thecoronaryarterybypassgraftwithanassistantgraftisfeasibletoimprovethelocalhemodynamicsanddiminishtheprobabilityofrestenosisinthetreatmentofcoronaryarterystenosis.

  • 标签: 冠状动脉 数值模拟 移植 旁路 计算流体动力学 嫁接
  • 简介:Thegraftcopolymerizationofacrylonitrile(AN)ontostarchundertheinitiationofpotassiumperman-ganatewasinvestigated.Theeffectofvariousreactionconditionsonthegraftcopolymerizationwasstudied.Therelationshipsbetweenthegraftingrateandtheinitiatorconcentrationofpotassiumpermanganate,monomeracuylonitrileandbackbonestarch,aswellasreactiontemperaturewereestablished.Theoxidationreactionofstarchwithmanganicionsandvalencechangesofmanganicionsduringthegraftcopolymerizationwerediscussed.TheresultsshowthatmanganicionMn^7+underwentaseriesofvalencechangesduringthegraftcopolymerization:Mn(Ⅶ)→Mn(Ⅳ)→Mn(Ⅲ)→Mn(Ⅱ).Thegraftingrateofthegraftcopolymerizationofacrylonitrileontostarchisalsogiven.

  • 标签: 淀粉 丙烯腈 接枝共聚作用 接枝率 高锰酸钾
  • 简介:

  • 标签:
  • 简介:BACKGROUND:Presently,over40kindsofduralgraftshavebeensuccessivelyusedinclinic.Amongthem,lyophilizedhumanduramaterwithgoodhistocompatibilityandlesscomplicationsisappliedmostwidely.Butthereareafewreportsoncasesofinfectedspongiformencephalopathyfollowingapplicationoflyodura.Moreidealrepairmaterialsdeservetobefurtherinvestigated.OBJECTIVE:Toinvestigatetheefficiencyandsafetyofbiologicalduralgraftmadebymeningesfromporkerstorepairmeningealinjury.DESIGN:Aself-controlobservation.SETTING:WuhanGeneralHospitalofGuangzhouMilitaryAreaCommandofChinesePLA.MATERIALS:SixteenNewZealandRabbits,ofeithergender,weighingfrom2to3kg,ofcleangradeⅡ,withtheageof0.5–1year,wereinvolvedinthisexperiment.TheinvolvedrabbitswereprovidedbytheAnimalExperimentalCenteroftheFirstMilitaryMedicalUniversityofChinesePLA.Biologicalsurgicalpatch(duralgraft)wasdevelopedbyGuangdongGuanhaoBiotechnologicalCo.,Ltd.Itwasprocessedbyusingmeningesfromporkersbytissueengineeringtechnology.METHODS:ThisexperimentwascarriedoutintheExperimentalCenterofthe157HospitalofChinesePLAbetweenDecember2003andJune2004.①Theexperimentalrabbitswereanesthetized.Duramaterwasexposedfromtwosidesofpostmediallineofcoronalsuture.Arectangularduramaterabout8mm×8mminsizewascutoff.Thenabiologicalsurgicalpatch(duralgraft)wasshearedintoinsertwith8mmdiameterandsutured.Theleftduramaterwasuntouchedandusedascontrol.Scalpwassutured,andpostoperativewoundhealingandrecoverywereobserved.②Theanesthetizedrabbitsweresacrificedatpostoperative3,14,30and90days,4rabbitsonce.Thewholeheadwascutoff,anditsscalpwasremoved.Afterwards,theheadwasfixedbyformalin.Tissuesinoperativesitewereobtained,performedroutineparaffinembedding,slicedandconductedHEstaining,finally,thesectionswereobserved.Whitebloodcellsinv

  • 标签: 肉用猪 脑脊膜 生物型硬脑膜移植片 应用 动物实验
  • 简介:Inthispaper,theradiationgraftcopolymerofMgO,SiO2andY-molecularsieveontoorganiccompounds,suchasmethacrylate,styreneandacrylomitrileobtainedbyper-radiationmethodwerecharacterizedbyX-raydiffraction,pyrolysisgaschromatography,GPCandX-rayphotoelectronspectroscopy.

  • 标签: 辐射接枝共聚物 无机化合物 烯烃 有机化合物
  • 简介:瞄准:与胃肠的graft-versus-host疾病(官方补给的GVHD)在病人评估内视镜检查法的诊断价值。方法:我们与官方补给的GVHD后面的allogeneic识别了8个病人造血的干细胞移植(HSCT)。GVHD组织学地被定义为腺apoptosis的存在,没由另外的煽动性或传染的病原学解释。结果:官方补给的GVHD的症状包括了厌食,恶心,呕吐,水泻,腹的疼痛,官方补给的流血,等等。上面的内视镜的外观从微妙的粘膜浮肿变化了,充血,红斑到明显的侵蚀。Colonoscopic检查显示出弥漫的浮肿,充血,补缀的侵蚀,散布溃疡,腐肉形成并且活跃流血。在官方补给的GVHD的组织学的变化在上皮和薄板propria包括了地窟上皮细胞,地窟的退学学生,和淋巴球的渗入的apoptosis。胃和书籍的右页冒号的参与从diffuse变化了到焦点。结论:内视镜检查法可以在跟随allogeneicHSCT的官方补给的GVHD病人的早诊断起一个重要作用,并且胃肠的活体检视的histologic检查被需要证实最后的诊断。

  • 标签: 内窥镜检查 胃移植 造血干细胞 诊断方法
  • 简介:Photoisomerization(trans-cis)ofazoaromaticcompoundshasbeeninvestigatedextensivelyusingabsorptionspectroscopysince1950s[1].Byirradiationwithlightofwavelengthλ1orλ2,thegeometricconfigurationoftheazobondinazobenzenebasedcompoundscanbereversiblyswitchedfromtranstocis.Thetwostateshavedistinctabsorptionspectra.Thisfeaturewouldallowreversiblestorageofdataonthebasisofcisandtransstateswiththeaidofλ1andλ2.However,thecisstateisthermodynamicallyunstablewithrespecttothetransstate,thereforeathermalrelaxationprocessoccursinthedark(atroomtemperature).Thisthermalback-reactionstronglylimitsthelifetimeofthecisstate,anditisinfluencedbythesubstituentR1andR2,catalysts,temperature,andenvironment(solventpolarity,typeofpolymermatrix)[2].

  • 标签:
  • 简介:Thestarch/D,L-lactidegraftcopolymersweresynthesizedbyreactingD,L-lactidewithcornstarchinN,N-dimethylacetamide(DMAM)inthepresenceoftriethylamine(NEt3)andanhydrouslithiumchloride.TheeffectofreactiontimeandthemolarratioofD,L-lactidetoglucosestructuralunitofstarchonmonomerconversion(C%),graft(G%)andgraftefficiency(GE%)werestudied,TheC%,G%andGE%couldapproach37.3%179.7%and68.0%,respectivelywhenthemolarratioofD,L-lactidetoglucosestructuralunitofstarchis10:1andthegraftcopolymerizationwascarriedoutat80-85℃for4hrundernitrogenatmosphere.TheFouriertransformsinfra-red(FTIR)spectroscopy.differentialscanningcalorimetry(DSC)andX_raydiffraction(XRD)spectroscopywereusedinordertocharacterizethegraftcopolymers.FTIRspectrashowthatabsorptionbandat1740cm^-1confirmedtheformationofesterbond,indicatingthestarch/D,L-lactidegraftcopolymerswereproduced,theDSCcharacteristicresultsshowthemeltingtemperatureofthegraftcopolymerwereelevatedslightlyasthemolarratioofD,L-lactidetoglucosestructuralunitsofstarchincreasedandtheX-raydiffractionspectrashowthesynthesizedgraftcopolymerswereamorphous.Thedegradabilityofgraftcopolymerwastestedwiththeaidofacid,alkaliandmicrobesuchasbacillussubtilisandstaphylococcusaureus.Theresultsofwaterrsistanceshowthegraftcopolymerproducedcanbeusedasacomponentofimpermeablecoatingforcardboard.

  • 标签: 聚合物 生物降解 玉米淀粉
  • 简介:Objective:Toinvestigatethemorphologicalcharacteristicsofthebridgetendongraftinginnoman'slandtoreconstructthetendondefectandtheeffectofpassivemobilizationonit.Methods:A2cmdefectwasmadeinbilateralflexordigitorumprofundustendonsofthemiddlechickentoes,andwasthentransplantedtotheoppositesitetoserveasasegmentalautografttendon.Postoperatively,passivemobilizationoftheleftandrightmiddletoesbeganat5and21dseparately.Specimenswerestudiedbylight,scanningandtransmissionelectronmicroscopyat5,10,21and35d.Results:Earlyrepairofthetendon-graftoftheleftmiddletoeswasmadebyproliferationandingrowthoftheepitenoncellsintermingledwithnewly-formedcollagenfibers.aglidingsurfaceformedat10and21d.Thetendongraftitselfplayedanactiveroleintherepair.Incontrast,adhesionsobliteratedthesurfaceandoccupiedthespacebetweenthetendongraftandsurroundingtissuesintherightmiddletoes.Conclusions:Itindicatesthattheuseofthesegmentalbridgetendongraftinnoman'slandcoupledwithearlypassivemotionstimulatesanintrisicrepairprocessinboththetendonstumpandtheautogenoustendongraftandresultsinafunctionalhealing.

  • 标签: 肌腱移植 动物实验 移植物
  • 简介:Surfacemodificationonapolytetrafluoroethylene(PTFE)panelwasperformedwithsequentialnitrogenplasmatreatmentsandsurface-initiatedpolymerization.ByintroducingCOO—groupstothesurfaceofthePTFEpanelthroughgraftingpolymerizationofacrylicacid(AA),atransparentpoly(acrylicacid)(PAA)membranewasachievedfromacrylicacidsolution.GraftingpolymerizationinitiatingfromtheactivegroupswasachievedonthePTFEpanelsurfaceafterthenitrogenplasmatreatment.Utilizingtheacrylicacidasmonomers,withCOO—groupsascrosslinksitestoformreticulationstructure,atransparentpoly(acrylicacid)membranewitharborescentmacromolecularstructurewasformedonthePTFEpanelsurface.Analysismethods,suchasfouriertransforminfraredspectroscopy(FTIR),microscopyandX-rayphotoelectronspectroscopy(XPS),wereutilizedtocharacterizethestructuresofthemacromoleculemembraneonthePTFEpanelsurface.AcontactanglemeasurementwasperformedtocharacterizethemodifiedPTFEpanels.ThesurfacehydrophilicitiesofmodifiedPTFEpanelsweresignificantlyenhancedaftertheplasmatreatment.Itwasshownthatthegraftingrateisrelatedtothetreatingtimeandthepowerofplasma.

  • 标签: 电感耦合等离子体 聚四氟乙烯膜 接枝聚合 丙烯酸 表面引发聚合 等离子体处理
  • 简介:AbstractBackground:Although the use of expanded-criteria donors (ECDs) alleviates the problem of organ shortage, it significantly increases the incidence of delayed graft function (DGF). DGF is a common complication after kidney transplantation; however, the effect of DGF on graft loss is uncertain based on the published literature. Hence, the aim of this study was to determine the relationship between DGF and allograft survival.Methods:We conducted a retrospective, multicenter, observation cohort study. A total of 284 deceased donors and 541 recipients between February 2012 and March 2017 were included. We used logistic regression analysis to verify the association between clinical parameters and DGF, and Cox proportional hazards models were applied to quantify the hazard ratios of DGF for kidney graft loss.Results:Among the 284 deceased donors, 65 (22.8%) donors were ECD. Of the 541 recipients, 107 (19.8%) recipients developed DGF, and this rate was higher with ECD kidneys than with standard-criteria donor (SCD) kidneys (29.2% vs. 17.1%; P = 0.003). The 5-year graft survival rate was not significantly different between SCD kidney recipients with and without DGF (95.8% vs. 95.4%; P= 0.580). However, there was a significant difference between ECD kidney recipients with and without DGF (71.4% vs. 97.6%; P = 0.001), and the adjusted hazard ratio (HR) for graft loss for recipients with DGF was 1.885 (95% confidence interval [CI] = 1.305–7.630; P = 0.024). Results showed that induction therapy with anti-thymocyte globulin was protective against DGF (odds ratio= 0.359; 95% CI= 0.197–0.652; P= 0.001) with all donor kidneys and a protective factor for graft survival (HR = 0.308; 95% CI = 0.130–0.728; P = 0.007) with ECD kidneys.Conclusion:DGF is an independent risk factor for graft survival in recipients with ECD kidneys, but not SCD kidneys.

  • 标签: Chronic kidney disease Delayed graft function Expanded-criteria donors Graft survival Standard-criteria donors
  • 简介:AIM:Toevaluatetheindications,complications,andvisualandgraftsurvivaloutcomesineyesthathadundergonesimultaneouscataractextractionandpenetratingkeratoplasty(PKP).·METHODS:Wedescribedaretrospectivestudyof101patientswhohadundergonesimultaneouscataractextractionandPKPatKingKhaledEyeSpecialistHospitalbetweenJanuary1,2001,andDecember31,2002.Allpatientswerefolloweduppostoperativelywithmaximumfollow-up68months.·RESULTS:Themeanageofpatientswas61years.Themeanoverallfollow-upwas27months.Themostcommonindicationsforsurgerywerecornealscarring(45.5%),previousfailedgraft(15.8%),cornealulcer(12.9%),Fuchsendothelialdystrophy(8.9%),stromaldystrophy(2.9%),andotherconditions(14.5%).Overall,69grafts(68.3%)remainedclearatfinalfollow-up.Previousglaucomaorpostoperativeglaucomahadnostatisticallysignificanteffectsongraftoutcome(P>0.05).Thegraftrejectionrate(17.8%)wasasignificantriskfactorforfailure(P=0.00).Age,gender,indicationsforsurgery,cornealgraftdiameter,andintraoperativevitreouslosshadnostatisticallysignificanteffectsonthePKPoutcome(P>0.05).Postoperativevisualacuitywassignificantlyassociatedwithpreoperativevisualacuity(P<0.01).·CONCLUSION:Thepresentstudyprovidesevidencethatperformingacombinedprocedureresultsinmorerapidvisualrehabilitationandgoodgraftclarity.

  • 标签: PENETRATING KERATOPLASTY CATARACT extraction GRAFT FAILURE
  • 简介:Therestenosisaftercoronaryarterybypassgraft(CABG)isattributedtotheformationofintimalhyperplasia(IH)attheanastomosis,whichiscloselyrelatedtohemodynamicdependonthegeometricmodel.Inordertogiveareasonableassessmentofthesurgeryeffectandjudgethelong-termpatencyrate,thehemodynamicofCABGsurgeryprogramiscomparedwiththatofsurgerydesignofthejunctionanglechanged.Basedonin-vivoCTcoronaryangiographydatasets,theindividualgeometricmodelofCABGreconstructedinsteadofidealizedgeometricmodelsareappliedtosimulatetherealphysiologicalbloodflowutilizingpulsatileflowboundarywaveformsinthepresentstudy.Thesimulationresultsshowthatthemaximumwallshearrate(WSS)valueisatthebottomofanastomosis.Moreover,thestagnationzonegrowinggraduallywiththegreaterangledownstreamtheanastomosisispronetoformtheIH,whichisconsistentwithclinicalobservation.Itisprovedthatthesurgerybeingbettersuitedtomaintaingraftpatencyissuccessful.

  • 标签:
  • 简介:客观现在的学习瞄准了进一步全面功能,对用老鼠的外部神经新生的histomorphometrical和immunohistochemical评价臀部的神经横断模型。方法10公里老鼠臀部的神经差距在老鼠被创造。在控制组神经树桩是到邻近的肌肉的sutured,在治疗组,差距被衔接用一在内外面静脉接枝。在假冒操作组,神经被操作并且留给未经触动。所有动物经历了在外科以后走轨道分析测试4,8,和12星期。随后,肌肉团测量被执行估计虚弱,词法上观察臀部的神经新生的组织学的考试和用反S-100检测Schwann房间的Immunohistochemistry。结果与二个在题目之间因素用因素的ANOVA被分析。为pairwise比较的Bonferroni测试被用来检验处理的效果。myelinated神经纤维的功能的分析显示出的结果那神经功能在处理在时间功课显著地改善了组。然而,myelinated神经纤维的量的morphometrical分析证明在处理组的8和12个星期之间没有重要差别。肌肉重量比率更大,gastrocnemius肌肉的重量损失被改善由在内外面静脉grafting。积极immunohistochemical反应的位置进一步暗示那改革了轴突,在静脉grafting被执行以后,Schwann像房间的细胞存在,并且被myelination的过程和改革神经的结构的恢复伴随。外部神经修理的结论功能的分析比量的morphometrical分析更加可靠

  • 标签: 坐骨神经 静脉移植 大鼠 功能恢复 周围神经再生 免疫组织化学
  • 简介:与钾每硫酸盐(KPS)作为开始者,ethylacrylate(EA)的接枝共聚化合物在水介质被调查到水溶性的hydroxypropyl纤维素甲醚(HPMC)上。grafting(G)和grafting效率(G_E)的百分比上的单体集中,开始者集中,矩阵集中,和反应温度的效果被学习。结果显示出价值两个都增加与的那G和G_EEA集中andKPS集中的增加;当从0提起HPMC集中时。12mmol/L到0.47mmol/L,G减少,当G_E增加时;并且当从50℃提起反应温度到65℃时,G增加,但是G_Edecreases。另外,接枝共聚物被Fourier变换描绘红外线(英尺红外)系列和传播电子显微镜学(TEM)方法。

  • 标签: 接枝共聚 乙烷基丙烯酸脂 羟基丙基甲基纤维素 过硫酸钾 引发剂
  • 简介:在分数之间的关系在风险分数系统(RSS)获得了的AIMTo分析与渗透keratoplasty(PKP)由希克斯等求婚了在1y的接枝失败手术后地并且在在有PKP接枝失败的风险的RSS的每个因素之中使用univariate和multivariateanalysis.METHODSThe有的回顾的队学习152从152个病人的PKP。十八个盒子由于主要失败(10个盒子)从我们的学习被排除,不完全的医药笔记(5个盒子)和后续不到1y(3个盒子)。我们从134个病人包括了134PKP在外科手术前的风险分数成层。枪兵系数在1y为在获得的分数和失败的风险之间的关系被计算。Univariate和multivariate分析为在1y.RESULTSSpearman系数在接枝失败上在RSS包括的每个单个风险因素的影响被计算在在RSS和接枝失败的分数之间的显示出的统计上重要的关联(P<0.05)。Multivariate逻辑回归分析没显示出统计上重要的关系(P>0.05)在有接枝失败的诊断和透镜地位之间。在因素学习了的另外的风险和接枝失败之间的关系是重要的(P<0.05),尽管以前的接枝的结果和接枝失败是不可靠的。这样,任何一个都没我们的病人有以前的输血它没有impact.CONCLUSIONAftermultivariate分析技术的申请,一些风险因素不在1y在接枝失败上显示出期望的影响。

  • 标签: 渗透 keratoplasty 接枝失败 20