简介：Ifyouwish/…tobeinformedabouttheoretiealandaPPliedresearehonaeuPunetureandMoxibustioninChina,/…toreadthelatestimportantartieleswrittenbyChineseaeupunetureandMoxibustion印eeialists,/.…tolearnreeent

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简介：AbstractBrucellosis is an important zoonotic infectious disease and is an important public health problem that causes serious economic consequences to the livestock industry. Brucella spp. comprise one of the most common pathogens causing laboratory-acquired infections (LAIs) and are becoming an increasingly important biosafety issue. To understand the significance of Brucella LAIs in China, related papers were search based on three Chinese databases (CNKI, Wanfang, and VIP), as well as PubMed. After assessment, 37 total cases were evaluated, including 27 students, seven laboratory technicians (one pregnant), two housekeeping staff, and one instructor. The age, sex, incubation period, pathogen detection results, and potential routes of infections were collected and analyzed. All LAIs occurred due to improper operations, inadequate biosafety training, and substandard laboratory safety conditions. Therefore, it is urgent to establish a comprehensive and systematic biosafety prevention/control system in laboratories to protect staff members from accidental exposures and LAIs; further, possible risks and control measures for the management of such infections were proposed.

简介：AbstractGonorrhea is one of the main sexually transmitted diseases in China. It mainly affects the genitourinary tract, and its clinical manifestations vary from asymptomatic to complicated types. The diagnosis of gonorrhea should be based on the patient’s epidemiological history, clinical manifestations, and laboratory examination results. Treatment should be prompt and standardized and should involve the recommended treatment regimens. Patients should be appropriately followed up after treatment. The antimicrobial resistance of gonococcal isolates has become a severe problem of clinical concern. In order to provide technical guidance of the diagnosis and treatment of gonorrhea for health care workers, the authors developed the guidelines based on the version of 2014, which will be of important in the standardizing medical care of gonorrhea, and further facilitating control and prevention of the disease.

简介：AbstractIn this study, we explored the viral diversity and community structures of the ticks collected from dogs and detected possible tick-borne viruses (TBVs) using metagenomic analysis. Additionally, full-length sequences and the structural, phylogenetic and molecular features of the possible TBVs were characterized using bioinformatics tools. The sequence run produced 12,254,268 reads and 6,667,259 unique reads from the tick pools. Further analysis of the viral reads revealed that 92.73% were similar to ssRNA viruses, and 90.5% of the total viral sequences belonged to Non-classified viral families. Of the 29 classified viral families, most virome sequences were homologous with vertebrate viruses from Circoviridae, plant viruses from Virgaviridae, phages from Microviridae, insect viruses from Baculoviridae, and giant viruses from Mimiviridae. In the process of assembly of reads, large contigs representing four virus families were identified, including Phenuiviridae, Chuviridae, Parvoviridae and Non-classified families. Some sequences of Non-classified family shared a highly divergent amino acid sequence identities from existing virus sequences. The importance of these newly identified virus contigs to public and veterinary health needs additional researches. Because of the lack of the acquired viral reads from these families, we only demonstrated the complete sequences of Circoviridae in detail. The complete canine circovirus (CaCV)-NC21 genome detected from police dogs was 2,063 bp long with a GC content of 53.6%. Our results suggested that tick viromes collected from dogs contained diverse sequences with a broad range of animal, insect, plant, and phage viruses, which may reflect the ecological characteristics of the dogs and their ticks. Furthermore, our study revealed the existence of the partial contigs belonging to the four virus families in ticks. More researches are needed to verify their importance to public and veterinary health. As well, our detection of CaCv-NC21 demonstrated that ticks can harbor and potentially transmit canine circoviruses.

简介：AbstractVitiligo is a common depigmented skin disease that negatively affects the physical and mental health of patients. The 2018 version of the Vitiligo Treatment Consensus has been updated based on the research progress on vitiligo in the past 3 years in combination with the clinical experiences of experts. The newly revised points include maintenance therapy, early glucocorticoid intervention, and oral mini-pulsed glucocorticoid administration protocols. The prospect of using JAK inhibitors in the treatment of vitiligo is also discussed.

简介：Objectives:TounderstandtrendsandepidemiologicalfeaturesofsyphilisovertherecentyearsinChinaandprovideascientificbasisfordevelopingpreventionstrategies.Methods:From1985to2000,syphiliscase-reportingdatacollectedfromallprovinces,autonomousregionsandmunicipalitieswereanalyzedbyapplyingepidemiologicalmethods.Results:(1)Epidemictrends:syphilisincidencehassteadilyriseninChinafrom1985to2000,especiallyafter1993,whenitassumedanexponentialgrowthpattern.80,406casesofsyphiliswerereportedinthecountryin1999,whichwasalmost40timesthenumberreportedin1993.Duringtheperiodof1993-1999,theannualaveragegrowthofthesyphilisincidenceratewas83.55%.Perhapsduetoarecentnationallawenforeementcampaign,thenumberofreportedsyphiliscasesdroppedslightlyin2000.(2)Geographicaldistribution:Syphilisspreadfromcoastal,""open""cities(especiallysomecitiesinFujianprovince)toinlandurbanareas,thentoruralareas.RegionswithahighincidencerateofsyphilisinChinaweretheMinjiang,Yangtze,andZhujiangRiverDeltas,BeijingandTianjinmunicipalities,andNortheastChina.Therewasasignificantdifferenceofsyphilisincidenceratesandgrowthratesbetweentheseareas.Aseriousepidemicoccurredinsomeareas,withanincidenceratereachingover200casesoutof100,000.(3)Populationdistribution:theratioofmaleandfemalecasesgraduallychangedfrom1.57:1in1993to1.02:1in2000.Theratewasthehighestinthe20-29agegroupandthelowestin10-14agegroup.Agreatdifferenceexistedinprevalencebetweendifferentpopulationgroupsanddifferentareas,andsomeareaswithseriousepidemicshadhighprevalenceratesevenamoungthegeneralpopulation.(4)Clinicalstageofsyphilis:Primaryandsecondarysyphiliscaseshavebeendominatingwithapercentageof90%ofallsyphiliscases.Primarysyphiliswasthemostcommoninmalesandsecondarysyphilisinfemales.Secondaryandlatentsyphilisc

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简介：ObjectiveTo调查军事人员在位于不同区域的中国army.MethodsEleven军人撤退医院里支撑的眼睛损害的流行病学的特征为这研究被选择。我们考察了在2005年1月和2009年12月之间的军事人员支撑的眼睛损害的所有医药记录。Patients’信息是镇定的。所有数据被放进数据库并且statistically.ResultsTotally分析了有有眼睛损害(442只眼睛)的415个住院病人，他们的吝啬的年龄是24.40年。眼睛损害在这研究说明13.51%所有眼睛疾病。从2006～2009，眼睛损害的数字在他们之中逐渐地增加了，(42.17%)175在空闲被伤害预定，并且(34.94%)145在工作预定。22(5.30%)病人们在损害前有一个眼睛手术或眼睛疾病的历史。总共，246个病人(59.28%)在24个小时以内被送到撤退医院，(56.64%)64在损害以后在24个小时经历了手术。有389个病人(93.73%)，在1次就医。187只眼睛(42.31%)的视觉尖酸是等级1(5=20/40)在损害以后。什么时候排出，349只眼睛(78.96%)获得了在中国军队的很经常的发生和更多注意应该被付阻止它的损害有的等级1.ConclusionEye的视觉尖酸。

简介：AbstractWith the changing lifestyle and the acceleration of aging in the Chinese population, the incidence and mortality of colorectal cancer (CRC) have risen in the last decades. On the contrary, the incidence and mortality of CRC have continued to decline in the USA since the 1980s, which is mainly attributed to early screening and standardized diagnosis and treatment. Rectal cancer accounts for the largest proportion of CRC in China, and its treatment regimens are complex. At present, surgical treatment is still the most important treatment for rectal cancer. Since the first Chinese guideline for diagnosis and treatment of CRC was issued in 2010, the fourth version has been revised in 2020. These guidelines have greatly promoted the standardization and internationalization of CRC diagnosis and treatment in China. And with the development of comprehensive treatment methods such as neoadjuvant chemoradiotherapy, targeted therapy, and immunotherapy, the post-operative quality of life and prognosis of patients with rectal cancer have improved. We believe that the inflection point of the rising incidence and mortality of rectal cancer will appear in the near future in China. This article reviewed the current status and research progress on surgical therapy of rectal cancer in China.

简介：Ifyouwish......tobeinformcdabouttheoreticalandappIiedresearchonacupuncturcinChina,......toreadthelatcstimportantarticleswrittenhyChincseacupuncturespeciaIists,......toIearnrecentadvanccsincIinicaIapplicationofacupunctureinmedicalinstitutesthroughoutChina,......topromotescientificcxchangcswithChineseacupuncturcspecialistsandrelatedmedicaIestab-lishments.

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简介：AbstractBackground:Moyamoya disease (MMD) is a relatively important and common disease, especially in East Asian children. There are few reports about EEG in children with MMD in China till now. This study is aimed to analyze the electroencephalographic features of MMD in pediatric patients in China preliminarily.Methods:Pediatric patients with MMD who were hospitalized in Peking University International Hospital and Beijing Tiantan Hospital from January 2016 to December 2018 were collected. Clinical and electroencephalography (EEG) findings were analyzed retrospectively.Results:A total of 110 pediatric patients with MMD were involved, and 17 (15.5%) cases had a history of seizure or epilepsy. Ischemic stroke was associated with a 1.62-fold relative risk of seizure. A subset of 15 patients with complete EEG data was identified. Indications for EEG in patients with MMD included limb shaking, unilateral weakness, or generalized convulsion. Abnormal EEG was seen in 14 (93.3%) cases, with the most common findings being focal slowing 12 (80.0%), followed by epileptiform discharge 10 (66.7%), and diffuse slowing 9 (60.0%). "Rebuild up" phenomenon on EEG was observed in one patient.Conclusions:Seizure and abnormal background activity or epileptiform discharge on EEG were common in pediatric patients with MMD. EEG may play a role in differential diagnosis among the transient neurological events in MMD such as transient ischemic attack and seizure.

简介：Ifyouwish......tobeinformedabouttheoreticalandappliedresearchonacupunctureinChina,......toreadthelatestimportantarticleswrittenbyChineseacupuncturespecialists,......tolearnrecentadvancesinelinicalapplicationofacupunctureinmedicalinstitutesthroughoutChina,

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简介：Abstract:AcquiredImmuneDeficiencySyndrome(AIDS)isaninfectiousdiseasecausedbyHIV.Ithasbeenepidemicformorethan20years,butthereisnocureofit.HealtheducationandbehavioralinterventionsaresomeofthemosteffectiveapproachesinthecontrolandpreventionofAIDS.ChinaisoneofthecountrieswiththefastestgrowingHIVseroprevalencerate,andisfacingawidespreadepidemicofAIDS.Currently,high-riskpopulationssuchasindividualswithmultiplesexualpartnersandintravenousdrugusersarethemainfociofhealtheducationandbehavioralinterventionsinChina.Encouragingresultshavebeenobservedinmanyformsofhealtheducationandbehavioralintervention.Theapplicationofhealtheducationandbehavioralinterventionsmustemergefromscientificevidence,followaseriesofstrategies,becarriedoutfromvariousperspectives,andrequiretheparticipationofallsocietalcommunities.

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简介：目的了解福建汉族人群D2S44、D10S28、D4S163VNTR多态性，为亲权关系概率计算提供基因频率。方法采用美国Lifecodes公司提供的VNTR检测试剂盒，应用RFLP技术首次对福建省9个地市103名汉族无关个体进行D2S44、D10S28、D4S163VNTR多态性研究，并将所得基因频率与中国台湾、香港、新加坡等地区进行比较。结果福建汉族人群三位点VNTR呈高度多态性，其杂合率分别为88．6％、86．3％、90．6％，呈孟德尔经典遗传，分布符合Hardy-Weinberg平衡定律。结论福建、台湾、香港、新加坡华人互为比较，D2S44、D10S28位点基因频率没有显著性差别(P>0．500)。