简介:通过5-甲基-7-甲氧基异黄酮与盐酸羟胺的缩合制得中间产物4-苯基-5-(2-羟基-4-甲氧基-6-甲基苯基)异恶唑,然后经过光异构化反应合成了4-甲氧基-6-甲基-7a-苯基苯并吡喃并[2,3-b]氮丙啶-7-酮,并采用IR,NMR,HRMS和单晶X-衍射分析对其结构进行了表征.单晶X-衍射分析结果表明:标题化合物属于单斜晶系,空间群P2(1)/n.在其晶体结构中,存在着氢键及芳香堆积作用,这些作用将标题化合物分子组装成了三维网络结构.
简介:Analternativerouteforthesynthesisof(-)-10-epi-ct-cyperone1startingfrom(+)-dihydrocarvone2isdescribedbyusinganasymmetricMichaeladditionasakeystep.Theroutefeaturesmoreefficientlyandcanbeperformedinlargescale.
简介:丙酰氯同四氢噻唑2硫酮及(R)四氢噻唑2硫酮4羧酸乙酯反应生成N酰基四氢噻唑2硫酮2a及光学活性N酰基(R)四氢噻唑2硫酮4羧酸乙酯2b,而α溴代丙酰氯分别同四氢噻唑2硫酮及(R)四氢噻唑2硫酮4羧酸乙酯反应得到四氢噻唑2α溴代丙酰硫酯3a及光学活性4乙氧羰基四氢噻唑2α溴代丙酰硫酯3b.用半经验的量子化学PM3方法研究了反应物和产物的电子结构和反应的焓变,得到了反应物1a异构化的过渡态.
简介:利用2,3-二甲基吡嗪与硝酸铜及氯化铜合成了铜配位聚合物[Cu(Mepz)]2n+(Mepz=2,3-二甲基吡嗪),并通过单晶X射线衍射方法进行了表征.该晶体属于正交晶系,空间群为:Cmca,相关晶胞参数为:a=0.68617(11)nm,b=1.3652(2)nm,c=1.9533(3)nm,V=1.8297(5)nm3.该配位聚合物中的Cu原子与2个N原子、2个O原子和2个Cl原子配位,形成了一个稍微畸变的配位八面体,每相邻的2个配体之间通过Cu离子与吡嗪环上的2个N原子配位连接成无限延伸的一维链状结构,并通过分子间的氢键作用进一步将其连接成为二维的超分子网络结构.
简介:利用基团拼合原理,将2,2′-联吡啶和硫醚结构引入到1,3,4-噁二唑母体结构中.以1,10-菲罗啉为原料,经过氧化、酯化、肼解以及环合等化学反应,合成了中间体2,2′-联吡啶-3,3′-二甲酰肼、2,2L联吡啶-3,3,-二(5-E1,3,4-噁二唑-2-硫酮])以及4个2,2L联吡啶-3,3′-二(5-E1,3,4-噁二唑-2-硫醚])系列目标化合物,其结构通过1HNMR和单晶X-射线衍射等进行表征.晶体结构分析表明:2,2′-联吡啶的3和3′位上取代基不同,2个吡啶环所在平面的偏转角度不同,1,3,4-噁二唑-2-硫醚结构能使2个吡啶环呈现较大的偏转角度.
简介:Theefficientcycloadditionreactionswerecarriedouttoaffordthenovel3,5-disubstituted-dihydroisoxazolesfrommethylundec-10-enoateandisoxazoles,triazoleandtetrazolo-triazolefrommethylundec-10-ynoate.Thereactionsoccurredunderrelativelymildconditionsandaffordedthedesiredproductsingoodyields.
简介:Threenewlanthanidephenoxyacetatecomplexeswith1,10-phenanthroline,[Nd(POA)3(phen)]2·2C2H5OH(1),[Eu(POA)3-(phen)]2·2C2H5OH(2)and[Sm(POA)2(DMSO)(phen)]2-(ClO4)2(3)(POA=phenoxyacetate,phen=1,10-phenanthroline,DMSO=dimethylsulfoxide),weresynthesizedandcharacterizedbyelementalanalyses,IR,UV-visandFAB-MSspectra.TheirstructuresweredeterminedbysinglecrystalX-raydiffractionanalysis.Incomplexes1and2,thecarboxlyategroupsarebondedtoLn^3+ioninthreemodes:thechelatingbidentate,thebridgingbidentateandthebridgingtridentate.Incomplex3,thecarboxylategroupsarebondedtoSm^3+iononlyinvolvedinonemode:thebridgingbidentate.Theluminescencebehaviorofcomplex2wasalsostudiedbymeansofemissionspectra.
简介:Twenty10-hydrocarbylacridonesand2-methylacridone,1-hydroxyacridoneweresynthesizedfromacridoneandcharacterizedbymp,IR,UV,1HNMRandMS.UsingNd:YAGasalasersource,thesecond-orderharmonicgeneration(SHG)valuesoftheacridonederivativesweremeasuredinpowderstateascomparedwithureapowder.TheresultsshowedthattheSHGvaluesofsomeof10-hydrocarbylacridoneswerehigherthanthatofurea,whileotherswerelower.Althoughthehydrocarbylsubstituents(R)attachedtonitrogenatomofacridoneweredifferentinsizeandelectronegativity,theyhadalittleeffectontheSHGvaluesof10-hydrocarbylacridones.Substituents,suchasmethylorhydroxygroupconnectedtothephenylring,causedalittleeffectontheSHGvalues,too,comparedwithacridone.TheabilityofRtopushelectrontowardthenitrogenatomortopullelectronfromthenitrogenatomplayanimportantroleonthemaximumwavelengthesofUV-visibleabsorptionofacridonederivatives.
简介:利用水热合成方法合成了2个新的配位聚合物[Ag(4,4′-bpy)(H2PO4)].2H2O(1)和[Cu4(L)8H4](2)(4,4′-bpy=4,4′-联吡啶,L=4-咪唑基苯甲酸),并通过元素分析、红外光谱和X-射线单晶衍射方法确定了该化合物的晶体结构.结构分析表明化合物1属于单斜晶系,P2/c空间群,晶胞参数a=8.4909(17)nm,b=8.7284(17)nm,c=18.498(4)nm,β=100.99(3)°,V=1.3458(5)nm3,Z=4,R1=0.0362,ωR2=0.0966.化合物1展示了一个一维的链式结构.化合物2属于单斜晶系,C2/c空间群,晶胞参数a=24.509(5)nm,b=18.957(5)nm,c=17.246(5)nm,β=119.807(5)°,V=6.953(3)nm3,Z=4,R1=0.0455(3564),ωR2=0.1519(6161).化合物2中存在着丰富的π…π堆积作用.
简介:Thesynthesisofanewtypeofhetero-macrocyclicpolyether2,3-henzo-1,4,7,13-tetraoxa-10-selenacyclopentadeca-2-eneisdeseribed.