简介：Situatedatthesouthernendoftheancientnorthernpoleofbio-geographicterrain,bycombingthenaturalgeographic

简介：AbstractThe incidence of septic acute kidney injury (AKI) is increasing, it has become a major threat to human health because of its acute onset, poor prognosis, and high hospital costs. The most common cause of AKI in critical-care units is sepsis. Septic AKI is a complex and multi-factorial process; its pathogenesis is not fully understood. In sepsis, the destruction of mucosal barriers, intestinal flora disorders, intestinal ischemia/reperfusion injury, use of antibiotics, and lack of intestinal nutrients lead to an inflammatory reactions that in turn affects the metabolism and immunity of the host. Such changes further influence the occurrence and development of AKI. New technology is enabling various detection methods for intestinal flora. Clinical application of these methods in septic renal injury is expected to clarify the relationship among pathogenesis, disease progression mechanism, and intestinal flora.

简介：Inthispaper,weusetheinterflowareaastheresearchobjectinthelogicalscienceparkforsoilandwaterconservationinJiangxiprovince;andthePaspalumnatatumanditslittercoverareusedasthegroundflora.WediscussesandanalysestheverticaldistributionofrunoffsoastoprovidetheoreticalsupportforthewideapplicationofthePaspalumnatatumforsoilandwaterconservationintheregionofredsoilinsouthChina.

简介：ThefloraandcommunityphysiognomyofdegradedplantationecosystemsonpurplesoilwereinvestigatedinNinghuaCountyofFujianProvince,Chinatounderstandtherelationshipbetweenplantdiversityandecosystemprocesses..Fourdifferentrestorationcommunities(labeledasecologicalrestorationtreatmentI,II,IllandIV)wereselectedbyspace-timereplacementmethodaccordingtotheerosionintensityindegradedpurplesoilecosystem.Theresultsshowedthatthereweretotally86plantspeciesbelongingto78generaand43familiesinthedegradedpurplesoilecosystem.Ofthe15typesofdistributionareainspermatophytegenus,12typeswerefoundinthepurplesoilecosystem.Alongrestorationgradientfromlowtohigh,plantgrowthtypeandlifeformspectrabecameabundantmoreandmore,andthespermatophytegeneraforeachdistributionareatypeandgeneranumbersfordifferentfoliagecharactersincreasedaswell.Itisconcludedthattheplantfloraandphysiognomyinecologicalrestorationprocessbecomemorecomplexanddiverse,indicatingthattheforestecosystemonpurplesoiltendstobemorestable.

简介：AccordingtothetheoryoftraditionalChinesemedicine(TCM),Qi(vitalenergy)isregardedasadrivingforceofbiologicalactivitiesinhumanbody,includingbothnutrientsubstancesandorganfunctions.Qi-invigoratingTCMsarewidelyusedtotreatvarioussymptomsanddisorders,suchasfatigue,obesity,immunosuppression,intestinalfloraimbalance,andgastrointestinaldiseases,inwhichQiisconsideredtobereducedordepleted.Interestingly,abundantclinicalevidencessuggestthatthesedisordersareassociatedwiththealternationofintestinalflora,whichdirectlyaffectsdiseasestatus.HereinwereviewtheinteractionbetweengutmicrobiotaandQi-invigoratingTCMsunderhealthyanddiseaseconditionsanddiscussthemechanismsofactionandapplicationsofQi-invigoratingTCMsinenhancinghealthstatusthroughmicrobialalternation.AbetterunderstandingoftheroleofQi-invigoratingTCMsinmodulatingmicrobialcompositionandtheassociationbetweenintestinalmicrobiotaanddiseaseswouldhelprevealtheclinicalconsequencesofmicrobiotaalterationandexploreopportunitiestoharnessthissymbioticrelationshiptoimprovepublichealth.

简介：广东省的Huadu植物群，华南包含lepidodendridLepidodendronshanyangense吴et他，它的通常认为的rhizophoreStigmariacf。ficoides(Brongniart)斯顿伯格；sphenophytes.lArchaeocalamitesscrobiculatus(Brongniart)Stur；bowmanitidSphenophyllumtenerrimum(Ettingshausen)Stur；pteridophyllSphenopterissp。不明确的分类位置；未经决定的蕨纲植物情报。etsp。nov；lyginopteridpteridospermRhodeopteridiumhsianghsiangense(Sze)张，赵et吴，trigonocarpoidpteridosperm由复叶代表了并且孤立Paripterisgigantea(斯顿伯格)的小鳍Gothan，Potonieasp的男结果实，和Trigonocarpussp的种子。生态地，早含碳(Visean)Huadu植被被划分成二个附近的社区：(1)近岸的hydrophilous“communityA”与支配Archaeocalamites和Rhodeopteridium；并且(2)湿森林“communityB”与支配灌木状的trigonocarpaleanpteridospermParipterisgigantea(斯顿伯格)Gothan和高像树的lepidodendridLepidodendronshanyangense吴et他。Huadu植被人相地类似于今日的低纬度的红树属植物森林。

简介：AbstractBackground:Tourette syndrome (TS) is a neuropsychiatric disorder with onset in childhood that warrants effective therapies. Gut microbiota can affect central physiology and function via the microbiota-gut-brain axis. Therefore, the gut microbiota plays an important role in some mental illnesses. A small clinical trial showed that fecal microbiota transplantation (FMT) may alleviate TS symptoms in children. Herein, FMT effects and mechanisms were explored in a TS mouse model.Methods:TS mice model (TSMO) (n = 80) were established with 3,3＇-iminodipropionitrile, and 80 mice were used as controls. Mice were grouped into eight groups and were subjected to FMT with feces from children or mice with or without TS, or were given probiotics. Fecal specimens were collected 3 weeks after FMT. 16S rRNA sequencing, behavioral observation, and serum serotonin (5-HT) assay were performed. Differences between groups were analyzed using Mann-Whitney U test and Kolmogorov-Smirnov (KS) tests.Results:A total of 18 discriminative microbial signatures (linear discriminant analysis score > 3) that varied significantly between TS and healthy mice (CONH) were identified. A significant increase in Turicibacteraceae and Ruminococcaceae in TSMO after FMT was observed (P < 0.05). Compared with non-transplanted TSMO, the symptoms of those transplanted with feces from CONH were alleviated (W = 336, P = 0.046). In the probiotic and FMT experiments, the serum 5-HT levels significantly increased in TSMO that received probiotics (KS = 1.423, P = 0.035) and in those transplanted with feces from CONH (W= 336.5, P = 0.046) compared with TSMO without transplantation.Conclusions:This study suggests that FMT may ameliorate TS by promoting 5-HT secretion, and it provides new insights into the underlying mechanisms of FMT as a treatment for TS.

简介：应用在IBM4341计算机上建立的Hansen摄动计算方法的软件，快速自动出了Flora群里五颗其周日平均运动n－997″小行星：（261）Prymno,(587)Hypsipyle,(753)Tifis,(783)Nora,(1598)Paloque和一颗n－975″小行星（855）Newcombia所受木星摄动的三角级数解，与过云用Bolin群法计算所得近似解作比较，因现在计及了（3E－10θ）长周期项和精化了（E－3θ）等主要周期项的系数，使得这些小行星普遍摄动计算的结果有了明显的改进。

简介：AbstractBackground:The incidence of idiopathic membranous nephropathy (IMN) has recently increased remarkably. Immune dysfunction caused by disordered intestinal flora might be an important factor affecting IMN. The Jian Pi Qu Shi Formula (JPQSF) shows promise in treating IMN. Here, we sequenced 16S rRNA genes to compare intestinal flora between patients with IMN and healthy persons. We also conducted a randomized controlled clinical trial to further compare the intestinal flora of patients with IMN treated with traditional Chinese medicine (TCM) and western medicine (WM).Methods:Among 40 patients with IMN treated at Department of Nephrology in Xiyuan Hospital, Chinese Academy of Traditional Chinese Medicine between July 2016 and December 2018, we compared 30 of them with 10 healthy persons (controls). The IMN group was randomly assigned to receive JPQSF (TCM) or immunosuppressant WM therapy in (n = 15 per group) for 6 months. Intestinal microbiota diversity was analyzed using alpha diversity and beta diversity. Intestinal flora that significantly differed between the groups was analyzed using MetaStat. The effects and safety of the therapies were determined based on the values for plasma albumin, 24-h urine protein excretion, serum creatinine, urea nitrogen, estimate glomerular filtration rate (eGFR), complete blood count, and liver enzymes. All data were statistically analyzed using Statistical Package for the Social Sciences (SPSS) 20.0 statistical software.Results:Baseline characteristics did not significantly differ between the IMN and healthy groups, or the TCM and WM groups. After six months of treatment, 24-h urinary protein significantly declined in the TCM and WM groups (before and after treatment: 3.24 ± 1.74 vs. 1.73 ± 1.85 g, P < 0.05 and 3.94 ± 1.05 vs. 1.91 ± 1.18 g, P < 0.05, respectively). Plasma albumin was significantly increased in the TCM group (before vs. after treatment: 32.44 ± 9.04 vs. 39.99 ± 7.03 g/L, P < 0.05), but did not significantly change in the WM group (31.55 ± 4.23 vs. 34.83 ± 9.14 g/L, P > 0.05). Values for urea nitrogen, serum creatinine, and eGFR did not significantly change in either group. The alpha diversity index for intestinal flora differed between the IMN and healthy groups, and the TCM and WM groups. Comparisons of multiple samples (beta diversity) revealed differences in intestinal flora between the IMN and healthy groups, and the TCM and WM groups. The Metastat analysis findings showed that the main genera that differed between the IMN group before treatment and the healthy group were Christensenellaceae_R-7_group, Bifidobacterium (77), Dorea, Escherichia-Shigella, Parabacteroides, Bifidobacterium, and Coprococcus_3. After TCM therapy, the main differential genera were Butyricimonas, Bacteroides, Alistipes, and Lachnospira, and after WM therapy, these were Ruminococcus_2, Lachnospiraceae_ND3007_group, Lachnospira, Bifidobacterium, Alistipes, and [Eubacterium]_ventriosum_group.Conclusion:Patients with IMN might have disordered intestinal flora, and JPQSF can regulate intestinal flora in patients with IMN.