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12 个结果
  • 简介:of ,customs ,for 

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  • 简介:<正>Atthe2011NationalFinancialWorkConference,itwasclearlypointedoutthatfinanceshouldcontinuetoservetherealeconomyandthatcapitalshouldbeensuredtobeinputtedintotherealeconomyinabidtoeffectivelysolvetheproblemsthatitwasdifficultandexpensivetofinance

  • 标签: BANKS LOANS TRANSFORMATION CREDIT FINANCE expensiv
  • 简介:(乙烯乙二醇)(GSSG-PEG-GSSG)glutathione-disulfide-endedpoly被设计。它为一个8arm-PEG-SH聚合物答案,和冻结的冻结比谷胱甘肽二硫化物(GSSG)是一台更有效的加速器时间能在生理的pH和温度从小时被调节到分钟。机制被建议解释GSSG和GSSG-PEG-GSSG冻结系统的不同行为。由于曾经去的thiol二硫化物交换反应,thiol二硫化物hydrogels也显示出有趣的胀大的行为。

  • 标签: 水凝胶 二硫键 二硫化物 交联 谷胱甘肽 GSSG
  • 简介:处理的大数据正在成为数据中心计算的固执己见者部分。然而,最近的研究显示了大数据工作量不能充分利用现代记忆系统。我们发现处理的大数据的戏剧的无效从缓存失误的庞大的数量和看情况的存储器存取的货摊。在这篇论文,我们介绍二优化处理这些问题。第一是slice-and-merge策略,它减少种类过程的缓存失误率。第二优化是direct-memory-access,它改革在钥匙/值的存储使用的数据结构。这些优化被评估与微基准并且真实世界的基准HiBench。结果我们的微基准清楚地以硬件事件计数表明我们的优化的有效性;并且HiBench的另外的结果显示出1.21X一般水准加速在上申请级。两结果说明那小心的硬件/软件合作设计将改进大数据处理的存储器效率。我们的工作已经集成于为ApacheHadoop的Intel分发。

  • 标签: 数据处理 内存系统 直接存储器访问 基准测试 Apache 高速缓存
  • 简介:电信级的企业IP电话解决方案朗讯Accelerate^TMVOIP企业解决方案面向大中型集团企业客户群,是具备高可靠性,高可扩展性的电信级IP通讯解决方案。该方案有效利用了IP网络的实用性和灵活性,为集团企业提供统一的、可控制的、功能丰富的通讯服务。作为集团企业理想的融合通讯解决方案,朗讯Accelerate^TMVOIP企业解决方案能够帮助企业提升运营效率、可靠性和安全性,简化网络管理,并且提高系统容灾能力。

  • 标签: 集团企业 企业解决方案 朗讯 客户群 运营效率 通讯服务
  • 简介:Sincethe18thNationalCongressoftheCommunistPartyofChina,GeneralSecretaryXiJinpinghasissuedaseriesofimportantexpositionsonpeaceanddevelopment,whoseimpactisincreasinglyimportantforthecurrentprocessofglobalgovernance.XihaspointedoutthatChinesecivilizationhasupheldharmonyinhandling

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  • 简介:One-dimensionalorderedwatermoleculesenteringandexitingfromacarbonnanotubewithanappropriateradiusarestudiedwithmoleculardynamicssimulations.Itcanbefoundthatawatermoleculenearthenanotubeendismorelikelytobeexpelledfromthenanotubeifitsdipoleisalmostperpendiculartothenanotubeaxis.ThekeytothisobservationisthatthosewatermoleculesareclosertothewallofthenanotubeawayfromtheequilibriumpositionoftheLennar-Jones(LJ)potential.Thus,theinteractionenergyforthosewatermoleculesisrelativelyhigh.Therearetwoparticularstructuresoftheperpendicularwatermoleculedependingonthedipoledirectionoftheadjacentwatermoleculeinthenanotube.Althoughtheprobabilitiesofthesestructuresarequitesmall,theircontributionstothenetfluxacrossthenanotubeendareapproximatelyequaltothepredominantstructures.Thepresentfindingsfurthershowthepossibilityofcontrollingthewaterflowbyregulatingthedipoledirectionsofthewatermoleculesinsidethenanochannels.

  • 标签: 碳纳米管 水分子 偶极子 分子动力学模拟 分子结构 相互作用能
  • 简介:EliminationoftheCRISPR/Cas9constructsineditedplantsisaprerequisiteforassessinggeneticstability,conductingphenotypiccharacterization,andapplyingforcommercializationoftheplants.However,removaloftheCRISPR/Cas9transgenesbygeneticsegregationandbybackcrossislaboriousandtimeconsuming.WepreviouslyreportedthedevelopmentofthetransgenekillerCRISPR(TKC)technologythatusesapairofsuicidegenestotriggerself-eliminationofthetransgeneswithoutcompromisinggeneeditingefficiency.TheTKCtechnologyenablesisolationoftransgene-freeCRISPR-editedplantswithinasinglegeneration,greatlyacceleratingcropimprovements.Here,wepresentedtwonewTKCvectorsthatshowgreatefficiencyinbotheditingthetargetgeneandinundergoingself-eliminationofthetransgenes.ThenewvectorsreplacedtheCaMV35SpromoterusedinourpreviousTKCvectorwithtworicepromoterstodriveoneofthesuicidegenes,providingadvantagesoverourpreviousTKCvectorundercertainconditions.Thevectorsreportedhereofferedmoreoptionsandflexibilitytoconductgeneeditingexperimentsinrice.

  • 标签: genome EDITING SUICIDE gene TRANSGENE KILLER
  • 简介:【摘要】利用COCA和BNC为主要(母语)英语语料库以及根据中国大陆出版的英文报刊,以“to accelerate the pace of”为例,对平卡姆女士在1998年出版的《中式英语之鉴》一书中列举的“中式英语”名词冗余的例子进行研究,描述其在母语语料库以及非母语英语语料中的使用情况,对现有中国时事政治用语翻译适用性较高,对于开展针对中国时政术语的英译研究具有一定参考意义。

  • 标签: 中式英语 语料库 名词冗余现象 汉译英
  • 作者: Jiang Qiao-Li Feng Shu-Jiong Yang Zhu-Ying Xu Qi Wang Shuang-Zhu
  • 学科: 医药卫生 >
  • 创建时间:2020-08-12
  • 出处:《中华医学杂志(英文版)》 2020年第15期
  • 机构:Department of Gastroenterology, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang 310012, China,Department of Gastroenterology, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310012, China,Department of Abdominal Medical Oncology, Institute of Cancer Research and Basic Medical Sciences of Chinese Academy of Sciences, Cancer Hospital of University of Chinese Academy of Sciences, Zhejiang Cancer Hospital, Hangzhou, Zhejiang 310022, China
  • 简介:AbstractBackground:Non-coding RNAs have attracted considerable attention for their vital role in cancer. The purpose of this study was to determine the effects of non-coding RNAs on hepatocellular carcinoma (HCC) and reveal their regulatory mechanism in the pathophysiological process.Methods:We measured the expression of mucin 1 (MUC1) and miR-485-5p in tissues from 15 HCC patients and in liver cancer cell lines by quantitative real-time polymerase chain reaction and Western blot, screened for aberrantly expressed microRNAs (miRNAs) by miRNA microarrays. Bioinformatics tools were used to find the miRNA and circular RNA that regulated MUC1, which were validated by RNA immunoprecipitation assay and luciferase reporter assay. Cell counting kit-8, Transwell assays, and flow cytometry were used to conduct functional experiments. Proteins were examined by western blot and immunohistochemical staining assays. Significant differences between groups were estimated using the one-way analysis of variance. A P < 0.05 was considered statistically significant.Results:MUC1 was overexpressed in HCC tissues compared with that in paratumor tissues (normal vs. tumor, 1.007 ± 0.215 vs. 75.213 ± 18.403, t = 18.401, P < 0.001) while miR-485-5p was down-regulated (normal vs. tumor, 4.894 ± 0.684 vs. 1.586 ± 0.398, t= 16.191, P < 0.001). Inhibition of miR-485-5p promoted cell proliferation (73.33% ± 5.13% vs. 41.33% ± 3.51%, t= 8.913, P < 0.001), migration (102 ± 8 cells vs. 46 ± 8 cells, t= 8.681, P < 0.001), invasion (59 ± 7 cells vs. 28 ± 2 cells, t = 8.034, P < 0.01), and suppressed apoptosis (22.64% ± 6.97% vs. 36.33% ± 3.96%, t = 2.958, P < 0.05) of HepG2 cells with which MUC1 is knocked down. Mechanically, miR-485-5p binds to MUC1, while circHECTD1 binds to miR-485-5p, resulting in the indirect up-regulation of the MUC1 level.Conclusions:Our findings reveal that circHECTD1 facilitates HCC progression by sponging miR-485-5p to up-regulate MUC1.

  • 标签: Mucin 1 CircHECTD1 MicroRNA-485-5p Hepatocellular carcinoma Competing endogenous RNA
  • 简介:NorthwestAirlinesannouncedthatitwillacceleratetheretirementofitsremaining12DC10-30aircraftinservice.Theairlinesaidthatduringthenextsevenmonths,itwillreplaceDC10aircraftwithnewAirbusA330sandBoeing747-400

  • 标签: 中国 西北航线 Dc10飞机 亚太航线 配套设施