简介:LetL~2([0,1],x)bethespaceoftherealvalued,measurable,squaresummablefunctionson[0,1]withweightx,andlet■_nbethesubspaceofL~2([0,1],x)definedbyalinearcombinationofJ_0(μ_kx),whereJ_0istheBesselfunctionoforder0and{μ_k}isthestrictlyincreasingsequenceofallpositivezerosofJ_0.Forf∈L~2([0,1],x),letE(f,■_n)betheerrorofthebestL~2([0,1],x),i.e.,approximationoffbyelementsof■_n.Theshiftoperatoroffatpointx∈[0,1]withstept∈[0,1]isdefinedbyT(t)f(x)=(1/π)∫_0~πf((x~2+t~2-2xtcosθ)~(1/2))dθ.Thedifferences(1-T(t))~(r/2)f=∑_(j=0)~∞(-1)~j(_j~(r/2))T~j(t)foforderr∈(0,∞)andtheL~2([0,1],x)-modulusofcontinuityω_r(f,τ)=sup{||(I-T(t))~(r/2)f||:0≤t≤τ}oforderraredefinedinthestandardway,whereT~0(t)=Iistheidentityoperator.Inthispaper,weestablishthesharpJacksoninequalitybetweenE(f,■_n)andω_r(f,τ)forsomecasesofrandτ.Moreprecisely,wewillfindthesmallestconstant■_n(τ,r)whichdependsonlyonn,r,andτ,suchthattheinequalityE(f,■_n)≤■_n(τ,r)ω_r(f,τ)isvalid.
简介:Let{Y(t);t=(t1,t2)≥0}={Xk(t1,t2);t1≥0,t2≥0}k∞=1beasequenceoftwo-parameterOrnstein-Uhlenbeckprocesses(OUP2)withcoefficientsαk>0,βk>0.AFerniquetypeinequalityisestablishedandthesufficientconditionfora.s.l^2continuityofY(·)isstudiedbymeansoftheinequality.
简介:摘要目的分析2020年青海省风疹流行特点和流行风疹病毒(rubella virus, RV)基因特征,为当地优化和完善风疹防控策略提供科学依据。方法汇总国家法定传染病报告系统中的青海省2020年风疹发病数据,分析其流行病学特征;依托青海省麻疹/风疹实验室网络,采集并鉴定2020年疑似风疹暴发和散发病例咽拭子标本,阳性标本盲传3代后获得RV分离株,提取病毒核酸后扩增并测定E1基因的739个核苷酸片段,用于鉴定2020年青海RV株基因型和亚型,并分析其与我国流行RV的分子差异。结果2020年青海省风疹发病呈现明显回升态势,发病年龄已后移至10~19岁年龄组青少年(占比94.9%);2020年从青海省4个风疹高发市州共分离到29株RV病毒株,经鉴定所有RV株均属于2B-L2c基因亚型,也是目前我国RV流行的优势基因亚型。此外,病毒学监测数据显示,2020年青海省存在着不同的2B-L2c基因亚型RV传播链,且一起暴发疫情可能由不同的传播链病毒引起。结论2020年青海省流行RV为2B-L2c基因亚型,该病毒的流行导致了青海省2020年风疹疫情的回升以及部分市州的暴发流行。
简介:目的探讨N(2)-L-丙胺酰-L-谷氨酰胺治疗重症患者肠功能障碍的效果.方法将96例重症并发肠功能障碍患者,随机分为观察组和对照组,每组48例,两组患者均在治疗原发病的基础上给予肠外营养治疗,观察组肠外营养液中加入N(2)-L-丙胺酰-L-谷氨酰胺0.4g/kg·d,对照组采用传统的肠外营养液,疗程均为10d.治疗前后采用LIFE评分及APACHE-Ⅱ评分对两组患者肠功能进行评估.结果治疗后,两组患者的LIFE评分及APACHE-Ⅱ评分均较治疗前降低,观察组患者降低较对照组明显,两组比较差异有统计学意义(P<0.05).结论重症患者肠功能障碍早期给予N(2)-L-丙胺酰-L-谷氨酰胺治疗,能有效地预防肠道黏膜萎缩,增强小肠和结肠黏膜细胞的活性,改善肠道的结构和吸收功能.
简介:ObjectivesTheeffectsofcarvediloloncalciumcurrent(ICa)wereinvestigatedinisolatedadultratventricularmyocytes.MethodsICawasrecordedbyusingwhole-cellpatch-clamprecordingtechnique.ResultsCarvedilolreversiblyinhibitedICainaconcentration-dependentmanner,carvedilolat0.1,0.3,1and10μmol/LintheextracellularsolutiondecreasedpeakICaby1.52%,18.04%,37.34%and72.18%,respectively.Thesteady-stateinactivationcurveofICawasshiftedtomorenegativepotentials,whiletheactivationcurvewasnotaltered.Therecoveryfrominactivationwasshiftedtorightdirection,itcouldnotberecoveredcompletely.Inaddition,Pretreatmentofventricularmyocyteswithprazosinandpropranololcouldn'tblockthecarvedilol-inducedreductionofICa.ConclusionsCarvedilolinhibitsICainadultratventricularmyocytesbymechanismsinvolvingpreferentialinteractionwiththeinactivatedstateofcalciumchannel.
简介:一新(2+1)维的格子方程被介绍在联合Toda格子和相对论的Toda格子(TL-RTL)的层次在开始的二个成员之上基于方程在(1+1)尺寸。为联合TL-RTLequations的层次的Darboux转变被构造。在联合TL-RTLequations的层次的开始的二个成员的答案,以及新(2+1)维的格子方程被theDarboux明确地获得转变。
简介:TwoseriesofterritremBanalogues(10a-10cand18)havebeendesignedandsynthesizedfromjujubogenin5awhichwaspreparedfromjujubogeninglycosides5bobtainedfromtheleavesofZizyphusjujuba.Thestructuresofthenewcompoundswereconfirmedby1H-,13C-NMRandMSdata.Compounds10cand18showedweakinhibitoryeffectonAChEat10^-4mol/E.