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  • 简介:Thispaperdealswiththeissueofprioritysettinginhealthcareunderuncertaintiesabouttheseverityoftheillnessandtheeffectivenessofmedicaltreatment.Weexaminetheeffectofadiseaseuncertainty(atreatmentuncertainty)ontheallocationofhealthcareresourcesinthepresenceofatreatmentrisk(adiseaserisk)andidentifypreferenceconditionsunderwhichthesocialplannerallocatesmoreresourcestohigherriskpopulation.Weallowforthesimultaneouspresenceoftworisksandinvestigatethejointeffectoftwo-sourceuncertaintiesonhealthcareallocationwhenthetworisksareeithersmallorpositivelyquadrantdependent.Theeffectofinequalityaversiononhealthcareallocationisalsoanalyzedbyintroducinganequityweightingfunction.Ourworkextendsthepreviousmodelofhealthcareprioritytotwo-riskframeworkandprovidesnewinsightsintotheproblemofhealthcaredecisionmakingunderuncertainty.

  • 标签: PRIORITY SETTING health care management RISKS
  • 简介:Venousmalformations(VMs)areproblematiccommonvascularmalformationsthatarechallengingevenforexperiencedphysicians.Severaltreatmentsareavailableincludingsclerotherapy,surgery,laserorcombinationsoftheseprocedures.Asnoneoftheseisspecific,westillneedtherapiesthatwouldallowtocurethesepatientswithoutcomplications.Hopefully,theunravelingofthecausativedefectsofVMswillgiveusnewtoolsforthemanagementofthisdifficultcondition.

  • 标签: 静脉畸形 治疗方法 手术治疗 病理机制
  • 简介:针刺内关.足三里.乳根和肩贞穴.温灸膻中.治疗了62例产后缺乳患者。经7次治疗.30例产妇乳汁分泌每天400mL以上.精神饱满;26例乳汁分泌每天250mL左右.需补充牛奶喂养婴儿;6例乳汁分泌无明显改善.挤压双侧乳房极少量乳汁分泌。

  • 标签: 针刺疗法 灸法 泌乳障碍
  • 简介:AbstractThe main treatments for Parkinson’s disease (PD) currently include surgery, rehabilitation, and most commonly, drug therapy. However, the drugs that are currently used to treat PD provide only symptomatic relief and delayed disease progression but have no curative effect and cause many adverse reactions. When considering pathogenic factors and metabolic regulation, PD and type 2 diabetes have a high rate of comorbidity; this provides a theoretical basis for the treatment of PD with first-line antidiabetic drugs. Among these agents, metformin reduces neuronal damage in the brains of PD patients via neuroprotection and the inhibition of oxidative stress and inflammatory responses, thus providing a novel strategy for the clinical treatment of PD. Here, we present the current state of knowledge about the use of metformin to treat PD and discuss its clinical prospects.

  • 标签: adenosine monophosphate-activated protein kinase metformin Parkinson’s disease signal pathway type 2 diabetes
  • 简介:Livermetastasessynchronouslyormetachronouslyoccurinapproximately50%ofcolorectalcancerpatients.Multimodalitycomprehensivetreatmentisthebesttherapeuticstrategyforthesepatients.However,theoptimalpatternofmultimodalitytherapyisstillcontroversial,anditraisesseveralsignificantconcerns.Liverresectionisthemostimportanttreatmentforcolorectallivermetastases.ThedefinitionofresectabilityhasshiftedtofocusonthecompletionofR0resectionandnormalliverfunctionmaintenance.Theroleofneoadjuvantandadjuvantchemotherapystillneedstobeclarified.Themanagementofeitherprogressionorcompleteremissionduringneoadjuvantchemotherapyischallenging.Theoptimalsequencingofsurgeryandchemotherapyinsynchronouscolorectallivermetastasespatientsisstillunclear.Conversionalchemotherapy,portalveinembolization,two-stageresection,andtumorablationareeffectiveapproachestoimproveresectabilityforinitiallyunresectablepatients.Severaltechnicalissuesandconcernsrelatedtothesemethodsneedtobefurtherexplored.Forpatientswithdefinitelyunresectableliverdisease,thenecessityofresectingtheprimarytumorisstilldebatable,andevaluatingandpredictingtheefficacyoftargetedtherapydeservefurtherinvestigation.Thisreviewdiscussesdifferentpatternsandimportantconcernsofmultidisciplinarytreatmentofcolorectallivermetastases.

  • 标签: COLORECTAL cancer LIVER METASTASES MULTIMODALITY THERAPY
  • 简介:Objective:ToinvestigatetherelationbetweennecrosisandapoptosisinthehippocampusofexogenousbFGFonthisprocess.Methos:WithMarmarou'smethodweproducedaseverediffusebraininjuryandstudiedthechangesinthehippocampusbyadaptingamodifiedTdT-mediateddUTP-biotinnickendlabeling(TUNEL)method.AtthesametimeweobservedtheeffectofexogenousbFGFonneuronalnecrosisandapoptosis.Results:WefoundthattogetherwithcellnecrosistherewasanincreaseinthenumberofapoptoticneuronsinthehippocampusCA2-3sectorsasearlyas4hafterinjury,withnumbersreachingamaximumat7d.ExogenousbFGFresultedinadefinitereductionintheamountofnecrosisandapoptosis.Conclusions:NeuronalnecrosisandapoptosisoccurincombinationafterbraininjuryandthatoneofthecausesmaybetheinsufficienceexpressionofthebFGFgeneinthehippocampusaftersevereinjury.ExogenousbFGFandsimilarsubstancemayproveclinicallyusefulafterbraininjurybyreducingcellnecrosisandapoptosis.

  • 标签: 脑损伤 BFGF 治疗 疗效 海马C2-3
  • 简介:DearEditor,IamDr.KhayWeiPohfromDepartmentofOphthalmology,HospitalKualaLumpur,Malaysia.IwritetoshareacaseofdiffusechoroidalhaemangiomainachildwithSturgerWebersyndromewhoshowedresolutionofexudativeretinal

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  • 简介:Objective:Toexploretherapeuticmethodforoccipitalneuralgia.Methods:Atotalof90occipitalneuralgiapatientswererandomlydividedintotreatmentgroup(n=60cases)andcontrolgroup(n=30).Intreatmentgroup,Dazhui(GV14)waspuncturedandstimulatedwithreinforcingmethod,andFengchi(GB20)puncturedandstimulatedwithreducingneedlingmethod.Incontrolgroup,thetenderpointwaspuncturedandstimulatedwithreducingneedlingmethod.Theacupunctureneedleswereretainedfor30minandthetreatmentwasconductedoncedaily,with10timesbeingatherapeuticcourse.Results:Afteronesessionoftreatment,themarkedlyeffectiveratesoftreatmentandcontrolgroupswere98%and57%respectively.Comparisonbetweentwogroupsshowedaconsiderabledifferenceinthetherapeuticeffect(P<0.05).Conclusion:AcupunctureofDazhui(GV14)andFengchi(GB20)areeffectiveinthetreatmentofoccipitalneuralgia.

  • 标签: 枕部神经痛 针灸疗法 GV 14 GB 20
  • 简介:BEIJING,July15(Xinhua)--ChinapledgeditwillabidebyWorldTradeOrganizationrulesandapply'samepolicies'tobothdomesticandoverseascompaniesinrareearthproduction,processingandexport.MinistryofCommercespokesmanYaoJiansaidChinanoticedthatrareearthpriceshavekeptrisingoverthepastfewyearsafterthecountryadjusteditsregulationsontherareearthindustrycoupledwithchangesintheinternationalmarket.

  • 标签: 稀土调控 中国 待遇 世界贸易组织 稀土生产 新华社
  • 简介:AccordingtothemethodofpuncturingthetwelveJing(well)acupointstotreathemiplegiafollowYinbai(SP1),Dadun(LR1),Shangyang(LI1)andGuanchong(TE1),combiningwithselectedacupointsaccordingtothepresentingsyndromes,totreat114casesofhemiplegiafollowingastroke,thetotaleffectiveratewas91.1%.

  • 标签: ACUPUNCTURE Therapy HEMIPLEGIA CEREBRAL Hemorrhage/complications CEREBRAL
  • 简介:在新ZWILAGnuclear浪费处理植物(瑞士)的不同踪迹元素和收音机核种的命运被建模,以便在植物预言并且检查不稳定的种类和他们的分发的运输行为。计算从药为活跃废物显示出那,工业,仅仅Zn和C有的研究(米尔浪费)在1200℃的稳定的气体的种类。调查证实清洗系统的检验烟道气体的效率。

  • 标签: 核污染 热处理 气体净化 示踪元素 重金属
  • 简介:Aim:Toexaminethetherapeuticeffectofacupunctureinthetreatmentofwithpseudobularparalysispatients.Methods:PseudobularparalysiswasconfirmedbyCTscanningexamination.Relevanttreatmentswereadministeredaftersyndromedifferentiation.Acupoints:Fengchi(GB20),Fengfu(GV16)andTaichong(LR3)werepuncturedandstimulatedwithuniformreinforcing-reducingmethodforsubduingtheliver-yangandeliminatingwind.UpperLianquan(RN23)andFenglong(ST40)werepuncturedandstimulatedbyreducingmethodforresolvingphlegmtoclearawayobstructioninthechannels.AcupointZusanli(ST36)wasadministeredwithreinforcingmethodtotonifyqi.Atreatmentcoursecomprisedof10sessions,with1to2days'internalbetweentwocourses.Eachcasereceivedatotalof20treatmentsessions.AcupointonthenechsuchasFengchi(GB20)wasadministeredwithretainingtheneedleinthesittingpositionfor10minutes.Results:Atotalof14caseswereobserved.After2coursesoftreatment,12cases(86%)werecured,onecase(7%)hadimprovementandtherestonehadnoapparentchanges.13cases(93%)hadtheirnagogastricfeedingtubesremoved.Conclusions:Ourexperienceshowedthatacupuncturetreatmentforpseudobularparalysistypeapoplexywassatisfactoryinthetherapeuticeffect.

  • 标签: 假延髓性偏瘫 针灸疗法 中风
  • 简介:Traumaticmultipleintracranialhematomas(TMICHs)areintracranialhematomas(ICHs)formedinmorethantwopositionsorwithmorethantwotypesafterheadinjury.1Thisarticlereports147casesofTMICHstreatedinourhospitalbetweenJuly1993andDecember1999.

  • 标签: 急性 创伤性颅内血肿 外科手术 疗效
  • 简介:Objective:Toobservethetherapeuticeffectofpreconditioningacupuncture(PA)onthetreatmentofprimarydysmenorrhea.Methods:Eightypatientssufferedfromprimarydysmenorrheawererandomlyassignedontheratioof1:1:2intothreegroups,20inGroupA,20inGroupB,and40inGroupC.GroupAandBweretreated

  • 标签: 针灸治疗 原发性 预处理 临床 治疗效果