简介：ObjectiveToreportoutcomesofcochlearimplantation(CI)inachildwithauditoryneuropathyspectrumdisorder(ANSD)andtoprovidepreliminaryclinicalevidenceoftheefficacyofCIinANSDpatients.MethodsA4-year-oldboywithdiagnosedauditoryneuropathyspectrumdisorder(ANSD)receivedimplantationofaNucleusCI24Rafteranunsatisfactorytrialofamplification.Post-implantationperformanceinbothhearingsensitivityandspeechrecognitionwasassessedindifferentsessions.Aidedhearingthresholdsweretestedbybehavioralaudiometry.MandarinEarlySpeechPerceptionTest(MESP),MeaningfulAuditoryIntegrationScale(MAIS),categoryofauditoryperformance(CAP)andSpeechIntelligibilityRating(SIR)wereusedtoassessthebenefitsinauditoryskillsorspeechrecognitiontheboyobtainedfromCI.Thetestswereadministeredbeforesurgeryandat3monthsand7monthsafteropening.ResultsTheboydemonstratedimprovedauditorysensitivitybyusingCI.Concerningspeechrecognitionandcommunication,bothspeechaudiometryandquestionnairesshowedanobviousbenefitfromCI.ConclusionsCIhasworkedefficientlyinthisANSDboy.ButbecauseoflimitedunderstandingofANSDandrehabilitationeffectbycochlearimplantationinthiscondition,theclinicaldecisiontoimplantshouldbecautiousandonlyafterathoroughevaluation.Meanwhile,wellcontrolledandlongtermstudiesareneededtoconfirmtheefficacyofcochlearimplantationinpatientswithANSD.

简介：BilateralCochlearimplants(CIs)improvedspeechintelligibility,speechperceptioninbackgroundnoise,andsoundlocalizationinquietandnoisysituations.However,itisunclearwhethertheseadvantagesessentiallyresultinbinauralintegrationofacousticstimulifromeachear.Inthisstudy,weinvestigatedtheeffectivenessofbinauralintegrationbybilateralCIsplacementusingbinauralhearingtestsandsubjectiveauditoryperceptualassessment.A61-year-oldbilateralCIssubjectunderwentthefollowingfourtests:theJapaneseHearinginNoiseTest(HINT-J),thedichoticlisteningtest(DLT),theRapidlyAlternatingSpeechPerception(RASP)test,andsubjectiveauditoryperceptualassessment.TheHINTJscorewassignificantlyhigherforbilateralCIsthanforaunilateralCI.However,DLTandtheRASPtestrevealedcontradictoryresults.Subjectiveauditoryperceptualassessmentrevealedactiveandbrightimpressionsforbilateralhearing,whichwerealsonoisyandstrongcomparedwiththoseforunilateralhearing.TheresultsofthisstudyrevealedthatbilateralCIsimprovedspeechperceptioninbackgroundnoiseandanimprovedauditoryimpression,althoughthebilateralintegrationabilitieswerenotimproved.ThiswasprobablybecausethepatientwasrequiredtocombineinformationfromthetwoearsintoasingleperceptioninDLTandtheRASPtest.Morelongitudinaldatashouldbecollectedandanalyzedinfuturestudiestoevaluatethelong-termeffectsofbilateralCIs.

简介：目的评估语前聋人工耳蜗植入患者的听觉言语康复效果，分析康复效果的相关影响因素。方法采用听觉行为分级标准（categoriesofauditoryperformance，CAP）和言语可懂度分级标准（speechintelligibilityrating，SIR），对50例语前聋人工耳蜗植入患者术后1年的听觉能力和言语能力进行分级评估；分析CAP和SIR结果与植入年龄、性别、侧别、术前助听时间、术后配戴方式、耳蜗是否畸形、康复模式、性格、康复时间等9个因素的关系。结果植入年龄、术前助听时间、康复模式、性格、耳蜗畸形、康复时间对CAP有显著影响；植入年龄、术前助听时间、康复模式、康复时间、性格对SIR有显著影响；性别、术后配戴方式、侧别对CAP和SIR均无显著影响。结论术前及早进行听力补偿及康复训练，有利于术后听觉言语能力的提高；家庭参与及教养方式对患儿康复效果有很大影响。

简介：由中国人民解放军总医院、北京协和医院、首都医科大学附属北京同仁医院和中国聋儿康复中心共同主办的第十届亚太地区耳蜗植入及相关科学会议（APSCI2015）将于2015年4月30日-5月3日在北京国家会议中心举行。APSCI是交流人工耳蜗及相关科学研究、发展和临床应用的国际性学术大会，这是APSCI在中国的第一次亮相，预计届时将有来自全世界各个国家的两千余位相关领域的专家学者参加此次盛会。我们期待中国的同道利用这个机会和来自世界各地的同行和学者讨论您的经验、进行深度互动。可以预见，APSCI2015将成为东西方科学及文化交融和碰撞的平台。

简介：摘要：目的 探讨强化随访在感音神经性耳聋患儿人工耳蜗植入术后语音康复护理的应用效果。方法 回顾性分析2019年1月至2020年4月在某院行人工耳蜗植入术治疗的112例感音神经性耳聋患儿的临床资料，根据护理方式不同为对照组（n=52）和观察组（n=60），对照组给予围术期常规护理，观察组在常规护理基础上实施语音康复护理强化随访，比较两组患儿术前、术后12个月时听觉能力分级（CAP）、交流方式及Nijmegen人工耳蜗植入量表（NICQ）评分的差异。结果 术后12个月时，观察组患儿CAP评分、NICQ量表中的心理功能、生理功能、社会功能评分均明显高于对照组，差异均有统计学意义（P

简介：【摘要】目的：研讨人工耳蜗植入术后患儿对其采取精细化护理的效果及满意度。方法：研究纳入了在2022年4月至2023年4月时间段内，自行前往我院的人工耳蜗植入术后患儿，共计有68例，分组方式为奇偶法，各34例，对比组实行常规护理，干预组实行精细化护理，干预组与对比组的护理前后指标及家长护理满意度评分实施组间对照。结果：人工耳蜗植入术后患儿护理前指标P值＞0.05，无差异。干预组人工耳蜗植入术后患儿护理后儿童焦虑量表、听觉能力分级较低、家长护理满意度评分高于对比组患儿，P＜0.05，有差异。结论：人工耳蜗植入术后患儿对其采取精细化护理效果明显。

简介：摘要听神经发育不良（cochlear nerve deficiency，CND）患儿可受益于人工耳蜗植入术（cochlear implantation，CI），但其术后听觉言语效果具有较大差异，目前还没有有效的临床工具来预测CND患儿CI术后效果。挑选适合人工耳蜗植入的CND患儿、植入侧别的确定以及术后听觉言语效果的预测一直是学术界的焦点、难点。本文就近年来有关评估听神经发育不良患儿人工耳蜗植入术后效果影响因素的研究进展做一综述，着重介绍影像及电生理学方面特点对CI术后效果影响特点的研究进展。

简介：【摘要】目的：探究预见性优质护理运用在人工耳蜗微创植入术病人中的有效性。方法：此实验选取在本院就诊的90例人工耳蜗微创植入术病人，研究时间为2019.7-2022.7，随机为病人分组，参照组、研究组各45例，前者运用常规护理方式，后者行预见性护理与优质护理干预，探究病人的手术时间、术中出血量以及并发症情况，观察比较结果。结果：研究组病人的并发症发生率低于参照组，P

简介：人工耳蜗是重度耳聋患者重建听力的惟一有效装置.虚拟通道是利用电流定向技术产生比已有电极数目更多的可感知的音调信息,不仅能提高噪声环境下的言语分辨率、音乐欣赏力,还可以提高汉语音调的识别率.

简介：AbstractBackground:Meniere’s disease (MD) is an idiopathic disorder of the inner ear, which manifests as cochleo-vestibular dysfunction. Hearing loss will progress to a profound levelin a subset of patients with MD, and vestibular interventions can independently cause loss of hearing. The aim of this study was to systematically review the published literature describing the safety and efficacy of CI in patients with MD.Materials and methods:A systematic literature review was conducted in accordance PRISMA guidelines to identify articles that assessed at least one functional outcome in patients with MD who underwent CI. Demographic information, disease history, MD symptoms, outcomes measures, and complications related to CI were extracted from included studies.Results:In total, 17 studies were included, and 182 patients with MD underwent CI. The weighted-mean age was 61.9 years (range 27-85). Study objective and methodology varied, and there was significant heterogeneity in CI outcome measures reported. In total, 179 (98.3%) of 182 patients reported objective improvements in at least one hearing metric after CI. A total of 69 patients (37.9%) reported vertigo or severe dizziness prior to CI, compared to 22 patients (15.4%) postoperatively. Two studies reported significant reductions in postoperative Tinnitus Handicap Inventory score (THI). Quality of life assessments varied between studies. Complications rates were low with only nine patients (4.9%) reporting a serious CI-related complication.Conclusions:This systematic review evaluated 17 studies describing the safety and efficacy of CI in patients with MD and encountered many challenges due to small sample sizes, and heterogeneity in study design and outcomes measured. Despite these limitations, this study of 182 patients is to the best of our knowledge the largest systematic review evaluating the safety and efficacy of CI in MD. The results of this study support the need for a standardized approach to evaluating outcomes of CI in patients with MD in future studies.

简介：Formanyyears,studiesaboutthecochleahavebeenmainlyfocusedonsensorycells,i.e.theinnerhaircell(IHC)andouterhaircell(OHC),andtheneuronsystem.Supportingcells,suchasHensen'scellsandDeiters'cellsarelessstudied.Theirphysiologicalfunctionsandothercharacteristicsarenotwelldocumented.Nowadays,supportingcellsareanewworldattractingtoscientists'interests.Thescopeofthisreviewistodetailthebiologicalpropertiesofthesupportingcells,mainlyHensen'scellsandDeiters'cellsinthecochlea.Studiesonthissubjectwillbehelpfulinunderstandingphysiologyofthecochlea,andhopefullyprovidenewapproachesintreatingdiseasesofinnerear.

简介：Globaldemographicchangesrelatedtolongevityareleadingtoincreasingnumbersoftheelderly,forwhomhearinglossisasignificantcauseofmorbidityanddisability.Oncemetwithreticence,severelyhearingimpairedolderadultsareincreasinglybeingconsideredforcochlearimplantation(CI).SignificantdataindicatethatCIintheelderlypopulationissafe,well-tolerated,andeffective.RisksfromCIsurgeryandanesthesiaarelowandgenerallycomparabletoratesinotheragegroups.OutcomesstudiesregardingCIinolderadultshaveshownexcellentimprovementstospeechperception,qualityoflife,andevencognition.Overall,currentlyavailabledatasuggeststhatadvancedageshouldnot,initself,beconsideredabarriertoimplantation.ThisreviewpaperwillhighlightselectedarticlesfromrecentmedicalliteratureregardingthesafetyandefficacyofCIintheelderlypopulation.

简介：AbstractWith cochlear implantation (CI) being the standard of care for profoundly deaf cases, more and more patients with low frequency residual hearing are currently being treated with CI. In view of preserving the residual hearing, the ultimate aim of both the surgeons and the CI companies is to achieve zero-degree of electrode insertion trauma. Variations in the size and shape of cochlea, cross-sectional dimensions of ST, electrode insertion techniques with and without metal stylet rod and the experience level of the operating surgeons, all play a role in the electrode array related insertion trauma. An effective electrode design must include flexible array to accommodate the cochlear shape variation, electrode with variety of array lengths to support the concept of cochlear size specific electrode array and finally smaller cross-sectional dimensions of electrode array in matching the cross-sectional dimensions of ST. As per published reports, FLEX electrode array design offers minimal degree of electrode insertion trauma along with the possibility of patient specific electrode array length matching their cochlear size. Looking at the cross-sectional dimensions of FLEX electrode array along with its volume, it appear to be highly safe to the cochlea by not taking too much volume inside the ST. To offer additional support, otological pre-planning software tool like OTOPLAN is now clinically available in measuring the cochlear size in finding the best electrode array match along with the possibilities of anatomy based post-operative speech processor fitting.

简介：Objective:Toreportcomplicationsrelatedtoflaparoundimplantsaftercochlearimplantation,possiblecausesofsuchcomplicationsandtreatments.Methodsandmaterial:Weperformedaretrospectiveanalysisofchildreninwhomcomplicationsrelatedtoflaparoundimplantsoccurredafterundergoingcochlearimplantationinourdepartmentfrom2005to2016.Results:Complicationsamong1500cochlearimplantation(CI)recipientsbythesamesurgeonincludedhematoma(n?20)andseromaaroundimplants(n?15),ofwhichmost(n?10)recoveredin2weeksaftereffectivedrainage,utilityofantibioticsandpressuredressing,but5developedflapnecrosisandhadtoundergocontralateralre-implantation.Fourpatientsdevelopedabscessaroundimplants,ofwhom2recoveredafter2weeksofdrainage,gentamicinirrigationanduseofantibiotics,but2patientsendedupwithflapnecrosisandhadtoreceivecontralateralreimplantation.Conclusions:Immediatedrainage,pressuredressingandantibioticscanbeusedtoeffectivelycontrolseromaaroundimplants.Forseromalastingformorethantwoweekswithoutimprovement,surgicaldrainagemaybeneed.

简介：Cochlearouterhaircells(OHCs)areinvolvedinamechanicalfeedbackloopinwhichthefastsomaticmotilityofOHCsisrequiredforcochlearamplification.Alternatively,amplificationisthoughttoarisefromactivehairbundlemovementsobservedinnon-mammalianhaircells.Wemeasuredthevoltage-evokedhairbundlemotionsinthegerbilcochleatodetermineifsuchmovementsarealsopresentinmammalianOHCs.TheOHCsdisplayedalargehairbundlemovementthatwasnotbasedonmechanotransducerchannelsbutbasedonsomaticmotility.Significantly,bundlemovementswereabletogenerateradialmotionofthetectorialmembraneinsitu.Thisresultimpliesthatthemotility-associatedhairbundlemotionmaybepartofthecochlearamplifier.

简介：【摘要】目的：针对人工耳蜗微创植入术患者临床护理中，采取预见性优质护理干预的效果。方法：2020年3月-2021年3月，在本院进行人工耳蜗微创植入术的患者人数为80例，患者被根据数表随机的方法分为参照组与实验组，参照组患者选取的护理方案为常规护理，实验组选取的护理方案为预见性优质护理干预，两组进行临床护理总有效率、手术基础数据信息的比较。结果：实验组临床护理总有效率高于参照组，P

简介：摘要：目的：探究不同干预模式在低龄语前聋患者中的治疗情况或康复效果，为其治疗方案的进一步选择提供参考依据。方法：以随机抽样原则为根本遵循，回顾性分析2018-2020年期间在我院接受双侧人工耳蜗植入（Cochlear implantation，CI）治疗的语前聋患者30例，以其为CI治疗组，然后于2021-2023年度，根据随机抽签结果，给予30例语前聋患者双模式干预，即单侧人工耳蜗植入、对侧助听器治疗（双模式干预组），在不同时间点（开机时、开机3个月、开机6个月和开机12个月后）对两组患者的听觉行为分级（CAP）、言语可懂度分级（SIR）、婴幼儿有意义听觉评分（IT-MAIS）、婴幼儿有意义言语评分（MUSS）以及言语空间听觉质量评分（SSQ-P）进行比较。结果：在治疗过程中，观察表1和表2的数据显示，两组患者的听力在开机时和开机3个月后都明显提升了。值得特别关注的是，双模式干预组的听力提升幅度明显超过了CI治疗组，但是随着时间的推移，到了开机6个月和开机12个月后，这种差异就不那么明显了，在这段时间内，双模式干预组的言语可懂度明显高于CI治疗组。就IT-MAIS和MUSS指标而言，两组患者在治疗过程中都表现出了改善趋势，在开机时和开机3个月后，双模式干预组的得分明显高于CI治疗组，这种差异在统计学上是显著的；然而，到了开机6个月和开机12个月后，这种差异却不再显著。结论：在短期内，双模式干预明显优于双侧人工耳蜗植入，有助于提升低龄语前聋患者的听觉、言语等能力，然而，长期效果方面，两种干预方法的差异较小，因此，临床医师在选择治疗方法时应该考虑患者的实际需求和疾病情况。

简介：Cochlearimplantationisoneofthebestamongstthevariousmanagementoptionsavailableforchildrenandadultswithseveretoprofoundsensorineuralhearingloss.Innerearandinternalauditorycanal(IAC)malformationsaccountstoapproximately25%ofcongenitalsensorineuralhearinglossinchildren.Theprimarygoalofthisreportwastoevaluatethecommunicationoutcomesaftercochlearimplantationinachildwithcysticcochleovestibularanomaly(CCVA).Thechildwasevaluatedthroughvariousstandardizedoutcomemeasuresatregularintervalstotracktheprogressintermsofauditoryandspokenlanguageskills.ThescoresonCategoriesofAuditoryPerception(CAP),MeaningfulAuditoryIntegrationScale(MAIS),SpeechIntelligibilityRating(SIR),MeaningfulUseofSpeechScale(MUSS),andlisteningandspokenlanguageskillsshowedasignificantleapin12monthsdurationpostimplantation.Thereportthushighlightsandcorrelatesthesignificantprogressinauditoryandspokenlanguageskillsofthechildwithcongenitalmalformationstoappropriateauditoryrehabilitationandintensiveparentaltraining.

简介：Objective:Neuronsinthecochlearnucleusshowdifferentresponsepatternstotheshorttonebursts.Becauseofthelimitationsofanimalexperiments,itishardtoexploretheprinciple.Therefore,usingamodeltosimulateCNneuronswillbeafeasibleway.Methods:Basedontheinitialmodelmentionedinthepreviousstudy,weproposedanimprovedCNmodelinMATLABR2012b.Results:Bymodifyingtheparametersofthemodelwefoundtheinterchangesamong"primary-like","chopper",and"onset"responsepatterns.Furthermore,wesimulatedthe"pauser"responsepatternbyaddinganextrainputinourmodel.Conclusion:TheresultsindicatethatthesynapticintegrationsandtheinputmodescangiverisetodifferentcharacteristicsofCNneurons,whicheventuallydeterminetheresponsepatternsofCNneurons.

简介：Objective:Acommoncavitydeformity(CCD)isadeformedinnerearinwhichthecochleaandvestibuleareconfluentformingacommonrudimentarycysticcavitythatresultsinprofoundhearingloss.Therearefewstudiespayingattentiontocommoncavity.Ourgroupisengrossedinobservingtheimprovementofauditoryandverbalabilitiesinchildrenwhohavereceivedcochlearimplantation(CI),andcomparingthesetargetsbetweenchildrenwithcommoncavityandnormalinnerearstructure.Materialandmethods:Aretrospectivestudywasconductedin12patientswithprofoundhearinglossthatweredividedintoacommoncavitygroupandacontrolgroup,sixineachgroupmatchedinsex,ageandtimeofimplantation,basedoninnerearstructure.CategoriesofAuditoryPerformance(CAP)andspeechintelligibilityrating(SIR)scoresandaidedhearingthresholdswerecollectedandcomparedbetweenthetwogroups.AllpatientsworeCIformorethan1yearattheCochlearCenterofAnhuiMedicalUniversityfrom2011to2015.Results:PostoperativeCAPandSIRscoreswerehigherthanbeforeoperationinbothgroups(p<0.05),althoughthescoreswerelowerintheCCDgroupthaninthecontrolgroup(p<0.05).TheaidedthresholdwasalsolowerinthecontrolgroupthanintheCCDgroup(p<0.05).Conclusion:EventhoughaudiologicalimprovementinchildrenwithCCDwasnotasgoodasinthosewithoutCCD,CIprovidesbenefitsinauditoryperceptionandcommunicationskillsinthesechildren.