简介:AbstractAvian influenza remains a threat to human wellbeing. Hypochlorite derivatives are commonly used as disinfectants to prevent the spread of the disease. The World Health Organization (WHO) has listed chlorine dioxide (ClO2) as an A1-level, safe, and efficient disinfectant. In this study, we tested the efficacy of ClO2, in aqueous solution and gas forms, against avian influenza A (H7N9) virus. The virus suspension was mixed with ClO2 aqueous solutions of various concentrations and for various time intervals. Aliquots of the mixture were then serially diluted, and the 50% tissue culture infective dose (TCID50) was measured with a hemagglutination test on MDCK cells. ClO2 gas produced from generators was introduced in a chamber containing the virus suspension in a Petri dish. The infective activity of the surviving virus was measured by the hemagglutination test. An aqueous solution of ClO2 at 126 µg/mL for 15 s was effective given that no surviving virus was detected with the hemagglutination test. ClO2 gas at >5 µL/L sustained for 1 h inactivated the virus effectively, while at 2.5 µL/L for 1 h, it only partially inactivated the virus. ClO2 as gas or aqueous solution at a certain concentration is effective in inactivating the H7N9 virus, and can be applied for the decontamination and disinfection of environments.
简介:目的及时了解国内外对新禽流感A(H7N9)的科研进展,把握防治禽流感A(H7N9)的主动权。方法及时收集国内外新发表的论文及报道,进行分析综合。结果初步证明了新禽流感A(H7N9)病毒的性质,基因特点,致病性,传播性,及其对药物的敏感性和防控要点。结论禽流感A(H7N9)病毒是一种三原重组的新病毒,对禽类及哺乳动物(包括人)都有致病性,且对人的毒性较强;但可防,可控,可治。目前对其认识还在随科研深入而发展,仍有不少不定因素,必须保持高度警惕,继续密切关注。
简介:摘要通过对H7N9型禽流感的病原学、流行病学特征、临床特点和我国内地H7N9型禽流感总体发病情况和疫情趋势研判,阐述了该疾病的基本情况,并提出了防控措施和应急处置流程。